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Identification of FXR1-associated protein complexes in lung cancer

Jun Qian - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The androgen receptor utilizes protein kinase docking sites to constitutively activate Elk1

Rayna Rosati - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Androgen Tear

Effects of metabolic stressors on cellular differentiation

Juan Manuel Schvartzman - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

5-Azacytidine

PIGU modulates radioactive iodine uptake in differentiated thyroid cancers

MORAN AMIT - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Sodium Iodide

Deubiquitinase Usp9x controls tumorigenicity through regulation of the Ets-1 transcription factor in melanoma

Harish Potu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Role of Kaiso in intestinal tumorigenesis

Manish K. Tripathi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Loss of 4E-BP1 function promotes EMT and metastasis via translational activation of snail

Qing Ye - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

FOXD3 is a novel repressor of the expression of short isoform of DCLK1 (DCLK1-S) from IntronV()-promoter of hDCLK1-gene, and is epigenetically silenced in hCRCs: prognostic/diagnostic implications of FOXD3/DCLK1-S expression in hCRCs

Malaney R. OConnell - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Impact of honokiol on sialylation in breast cancer cells

Padmamalini Thulasiraman - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

NPC-09

4E-BP1 hyper-phosphorylation senses microtubule damage and plays a critical role in taxane antitumor activity

Prashant Khade - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Seliciclib

Recurrent transcriptome alterations across multiple cancer types

Bogumil Kaczkowski - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Sumoylation of the retinoic acid receptor alpha protein represses transcriptional activity and contributes to retinoic acid resistance in glioma stem cells

Virginia W. Rodriguez - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Nuclear -arrestin1 is a critical cofactor of hypoxia-inducible factor-1 signaling in endothelin-1-induced ovarian tumor progression

Piera Tocci - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

endothelin-1

Nuclear localization of a secretion protein NAG-1/GDF15

Kyung-Won Min - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The alternative NF-kB2/RELB pathway is activated by LTB/LTB receptor and NIK to promote cell migration and metastasis-related gene expression in HNSCC

Rita Das - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Overcoming therapy resistance in SOX2-expressing head and neck squamous cell carcinoma cells by targeting the downstream BCL2-pathway

Hui Wang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Cisplatin

Biphenylene and bipyridine connected benzofuran compounds as novel regulators of kRAS transcription

Harshul Batra - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

N/A

Penfluridol suppresses glioblastoma tumor growth by inhibiting sonic hedgehog signaling

Alok Ranjan - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Temozolomide

Interaction between MUC1 and STAT1 drives IFITM1 overexpression in aromatase inhibitor-resistant breast cancer cells

Asona Lui - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Fulvestrant

Ultrasound-mediated neuropilin-1 shRNA minicircle delivery inhibits tumour growth in an orthotopic human pancreatic adenocarcinoma model

Pratiek N. Matkar - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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