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2901 : Nuclear -arrestin1 is a critical cofactor of hypoxia-inducible factor-1 signaling in endothelin-1-induced ovarian tumor progression

Researchers

Presenter

  • Piera Tocci

Principal Investigators

  • Roberta Cianfrocca

  • Laura Rosano

  • Valentina Caprara

  • Rosanna Sestito

  • Valeriana Di Castro

  • Anna Bagnato

Medical Centers

  • Regina Elena National Cancer Institute, Rome, Italy

Locations

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Ovarian cancer

  • Solid malignancies

Biomarkers

  • E1A Binding Protein P300

  • Endothelin receptor type B

  • Vascular endothelial growth factor A

Drug/Treatment

  • endothelin-1

  • macitentan

  • folitixorin calcium

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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