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2187 Abstracts

OUTCOME OF ALLOGENEIC STEM CELL TRANSPLANTATION IN ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS USING TOTAL BODY IRRADIATION BASED CONDITIONING VERSUS NON TOTAL BODY IRRADIATION BASED

Amr Gawaly - European Hematology Association (EHA) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Cyclophosphamide

Evaluate correlation between NUDT15 variants and 6‐mercaptopurine sensitivity in vietnamese pediatric acute lymphoblastic leukemia

T. H. Huynh - British Society for Hematology (BSH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Allmercap

Genetic and genomic characterisation of older adults with acute lymphoblastic leukemia treated on the UKALL14 and UKALL60 + clinical trials

T. Creasey - British Society for Hematology (BSH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

Cyclin D1 G870A polymorphism and its relation to the risk of ALL development, prognosis and methotrexate cytotoxicity

A. Elmarghany - British Society for Hematology (BSH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Methotrexate

Chemotherapy – Induced Thrombocytopenia in Pediatric Acute Lymphoblastic Leukemia: A Single-institution Report

M. Gizhlaryan - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

Generation of Megakaryocytes from Human Bone Marrow Aspirates as a Simple Diagnostic and Research Tool: Assay Development and Validation

K. Butov - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

L-Asparaginase Induced Hyperlipidemia, Pseudohyponatremia and Cerebral Venous Thrombosis during Acute Lymphoblastic Leukemia Remission Induction Therapy

H. Uzel - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Asparaginase

Polygenic Risk Score-Analysis of Thromboembolism in Patients with Acute Lymphoblastic Leukemia

K.B. Jarvis - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

Predictive Factors for Disseminated Intravascular Coagulation in Childhood Acute Lymphoblastic Leukemia

N. Songthawee - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

Severe Platelet Dysfunction in Patient with Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL) after Tyrosine Kinase Inhibitor (TKI) Therapy

M.R. Cozzi - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Imatinib

Thrombosis and Laboratory Monitoring in Children with Acute Lymphoblastic Leukemia

E. Seregina - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Thrombomodulin alfa

Lymphoma uteri: secondary infiltration of the uterus caused by primary malignant hematologic disease

B.L. Rakocevic Mesarovic - International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Human chorionic gonadotropin

Identifying low allele frequency somatic variants using the Saphyr System

Joyce Lee - American Association for Cancer Research (AACR) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

The NSD2 p.E1099K mutation is enriched at relapse and confers drug resistance in a cell context dependent manner in pediatric acute lymphoblastic leukemia

Joanna Pierro - American Association for Cancer Research (AACR) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

High-dose TSLP decreases in vivo tumor burden in preclinical models of CRLF2 B-ALL

Caleb Ruiz-Jimenez - American Association for Cancer Research (AACR) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-Jun N-terminal kinase inhibition

Xinhua Xiao - American Association for Cancer Research (AACR) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

dasatinib

MicroRNA-497~195 cluster suppresses acute lymphoblastic leukemia growth by targeting CCND3/CDK4 and inhibiting cell cycle progression

Elena Boldrin - American Association for Cancer Research (AACR) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Palbociclib

Potential of 6-mercaptopurine and 5-azacitidine in halting progression of poor prognosis residual disease in triple negative breast cancer

Balraj Singh - American Association for Cancer Research (AACR) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

6-mercaptopurine

Combinational strategy targeting B cell malignancy using iPSC engineered CAR-NK (FT596) and CAR-T cell (FT819) platforms with therapeutic antibody to achieve an effective deep and durable response

Jode P. Goodridge - American Association for Cancer Research (AACR) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Rituximab

Genomic analysis of infant KMT2A-r acute lymphoblastic leukemia reveals weak association with underlying germline cancer predisposition

Azhar Saeed - American Association for Cancer Research (AACR) , 2020

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

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