// App-Quantinova.ai

2541 : MicroRNA-497~195 cluster suppresses acute lymphoblastic leukemia growth by targeting CCND3/CDK4 and inhibiting cell cycle progression

Researchers

Presenter

  • Elena Boldrin

Principal Investigators

  • Enrico Gaffo

  • Judith Boer

  • Salih Demir

  • Julia Zinngrebe

  • Rainer Claus

  • Christoph Plass

  • Monique L. den Boer

  • Klaus-Michael Debatin

  • Geertruy te Kronnie

  • Stefania Bortoluzzi

  • Lder Hinrich Meyer

Medical Centers

  • University Medical Center Ulm, Ulm, Germany

  • Universita di Padova, Italy

  • Princess Maxima Center for Pediatric Oncology, Netherlands

  • Freiburg University Medical Cente, Germany

  • German Cancer Research Center (DKFZ), Germany

Locations

  • Germany

  • Italy

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Cyclin D3

  • Cyclin dependent kinase 6

  • Cyclin Dependent Kinase Inhibitor 2A

  • Cyclin Dependent Kinase Inhibitor 2B

  • Retinoblastoma protein

Drug/Treatment

  • Palbociclib

  • Decitabine

Outcome

  • N/A

Study Design

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved