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BSH2020‐PO‐017A : Genetic and genomic characterisation of older adults with acute lymphoblastic leukemia treated on the UKALL14 and UKALL60 + clinical trials

Researchers

Presenter

  • T. Creasey

Principal Investigators

  • E. Barretta

  • A. Kirkwood

  • C. Schwab

  • P. Patrick

  • L. Clifton-Hadley

  • B. Patel

  • T. Menne

  • A. McMillan

  • N. Morley

  • J. Snowden

  • C. Harrison

  • D. Leongamornlet

  • E. Papaemmanuil

  • C. Rowntree

  • D. Marks

  • A. Fielding

  • A. Moorman

Medical Centers

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Cancer Research UK and UCL Cancer Trials Centre, University College London, London, United Kingdom

  • Department of Haematology,Queen Mary University of London,London,United Kingdom

  • Department of Biochemistry, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom

  • Department of Paediatric Oncology, Nottingham University Hospitals NHS Trus, Nottingham, UK

  • Department of Haematology, Royal Hallamshire Hospital

  • Department of Clinical Oncology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield,

  • Sanger institute, Cambridge, United Kingdom.

  • Memorial Sloan-Kettering Cancer Center, New York, NY, United States

  • Haematology, Cardiff and Vale university health board, Cardiff, UK

  • Department of Haematology, University Hospitals NHS Foundation Trust, Bristol, United Kingdom

  • Department of Haematology, UCL Cancer Institute, London, United Kingdom

Locations

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Abelson murine leukemia viral oncogene homolog

  • Abelson murine leukemia viral oncogene homolog 2

  • Breakpoint Cluster Region

  • Paired box 5

  • Phosphatase and tensin homolog

  • Platelet Derived Growth Factor Receptor Beta

  • Colony stimulating factor 1 receptor

  • Cyclin Dependent Kinase Inhibitor 2A

  • Retinoblastoma protein

  • ETV6-RUNX1

  • Histone-lysine N-methyltransferase 2A

  • Immunoglobulin heavy-chain variable region gene

  • Neurofibromatosis type 1

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A