App-Quantinova.ai

Activation of phosphatase toward the retinoblastoma protein inhibits invasion in MDA-MB-231 breast cancer cells

Jacklynn Egger - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Doxycycline

CLCA2 interaction with EVA1 promotes mammary epithelial differentiation

Grace N.T. Ramena - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Notch4 mediates mesenchymal-epithelial-like transition in melanoma

Ehsan Bonyadi Rad - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Occlusal-HP Topical

Mesothelin regulates epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells

Xiaoqing He - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

IGF-1 and TGF- promote EMT and angiogenesis in 3D cultures of lung adenocarcinoma cells: A pilot study

Imad Tarhoni - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Mecasermin

TMPRSS2:ERG fusion enhances osteoblastic phenotype of prostate cancer bone metastases

Carine Delliaux - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Nicotinamide N-methyltransferase in clear cell renal cell carcinoma primary tumors and metastases

Anna Reustle - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Nicotinamide

Conjugated bile acids aggravate metastatic pancreatic cancer via sphingosine-1-phosphate receptor 2

Hiroaki Aoki - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

FTY720

Mitochondrial haplotype alters metastasis in a non-cell autonomous manner

Amanda E. Brinker - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Novel evidence that blood plasma vitronectin is a major chemoattractant for cancer cells and its pro-migratory activity is suppressed/chaperoned after binding to fibrinogen

Gabriela Schneider - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Fibrinogen (IV)

Protumoral role of trans fatty acid in colorectal cancer

Hitoshi Ohmori - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Adrucil injection

Novel microfluidic blood-brain niche to study breast cancer metastasis to the brain

Megan Altemus - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Expression of Hedgehog signals and growth inhibition by itraconazole in endometrial cancer

Kayo Inoue - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Itraconazole

STRAP mediates the stemness of human colorectal cancer cells by epigenetic regulation of Notch pathway

Lin Jin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

EZH2

Circulating tumor cells from in vitro 3D culture systems have tumor-initiating capacity in vivo

Marina C. Cabrera - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

CD133 attenuates ROS accumulation via a steady increase in the expression of the cystine/glutamate transporter xCT: Consequence on chemoresistance in hepatocellular carcinoma

Haengran Seo - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Role of SENP1 in HBx-induced cell migration and stemness-related properties in hepatocellular carcinoma

Te Sheng Chang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Pancreatic cancer stem cell metastasis and mitochondrial respiration is dependent on the the ISG15-mediated ubiquitin-like modification process known as ISGylation

Bruno Sainz - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Ribo-100

The significance of c-Kit proto-oncogene in iCSC-derived PDAC model

Anna Sanchez Calle - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

DCLK1 promotes tumor growth and invasion through Slug-mediated epithelial-mesenchymal transition in pancreatic neuroendocrine tumors

Yu Ikezono - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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