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1709 : STRAP mediates the stemness of human colorectal cancer cells by epigenetic regulation of Notch pathway

Researchers

Presenter

  • Lin Jin

Principal Investigators

  • Trung Tam Vu

  • Pran K. Datta

Medical Centers

  • University of Alabama at Birmingham, Birmingham, AL

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Colorectal Cancer

  • Ulcerative colitis

  • Solid malignancies

Biomarkers

  • Mitogen-activated protein kinase

  • Cluster of Differentiation 44

  • Prominin 1

  • Retinoblastoma protein

  • Enhancer of zeste homolog 2

  • Extracellular signal-regulated kinase

  • Trimethylation of lysine 27 on histone H3

  • MAPK/ERK

Drug/Treatment

  • EZH2

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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