App-Quantinova.ai

MiR-203 suppresses cutaneous squamous cell carcinoma growth and targets the myc oncogene

Warangkana Lohcharoenkal - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Up-regulated miR-96-5p inhibits apoptosis by targeting FOXO1 in hepatocellular carcinoma

Naoto Iwai - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

miRNAs are key mediators of crosstalk between estrogen and progesterone regulating breast cancer invasiveness

Thomas B. McFall - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Progestin

MicroRNA miR-31 regulates oral squamous cell carcinoma cell migration by targeting critical enzyme of peroxisomal lipid metabolism

Yi-Shiuan Lai - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Mir-223-5p works as an oncomir in vulvar carcinoma by TP63 regulation

Rafael Rocha - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

MicroRNA-211 enhances the oncogenicity of oral carcinoma through targeting TCF12 and up-regulating FAM213A expression

Yi-Fen Chen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Mir-194-3p suppresses tumorigenic potential of glioblastoma stem cells by targeting the canonical NF-kB pathway

Rajbir Singh - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The role of Epstein-Barr virus-encoded miRNAs in ATM regulating DNA damage response in nasopharyngeal carcinoma

RAYMOND Wai-Ming LUNG - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Solid malignancies

N/A

Differential expression of human cytomegalovirus microRNA in triple-negative breast cancer tumors

Tia Hudson - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

FGFR1 can act as an oncogene or a tumor suppressor depending on the molecular context

Alvaro Quintanal-Villalonga - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Expression of the lipocalin 2 oncogene in the development of smoking-associated and Kras mutant lung adenocarcinoma

Joshua Ochieng - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Interleukin

EGFR-mediated activation of RET in ASCL1+ lung adenocarcinoma

Kaustubh N. Bhinge - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

gefitinib

Regulation of CT120 gene as a new target of c-myc in head and neck squamous cell carcinoma (HNSCC)

Onur Baykara - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Prevalence of activated NOTCH receptor in solid tumors and chronic lymphocytic leukemia

Gerard Oakley - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

FYN expression potentiates FLT3-ITD-induced mitogenic signaling in acute myeloid leukemia

Rohit A. Chougule - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Arginine hydrochloride

Mutation and function of PIK3CA and HRAS in human oral squamous cell carcinoma cells

Hitoshi Akiyama - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Trametinib

Translational control of MYC protein stability as a target of small molecules

Naohiko Ikegaki - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Halofuginone

Pro-proliferative function of SIRT3 in a human melanoma xenograft mouse model

Jasmine George - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Solid malignancies

Nicotinamide

Zhx2 promotes survival of B-cell acute lymphoblastic leukemia cell lines

Namit Sharma - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

dasatinib

Enhancer of zeste homolog 2 (EZH2) inhibition in metastatic melanoma promotes tumor regression in vivo

Deepanwita Sengupta - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

EZH2

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