App-Quantinova.ai

NGS analysis of the single CTC or DTC isolated and subtyped by the integrated subtraction enrichment and immunostaining-FISH

Peter Lin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

High-throughput mutational analysis in cell-free DNA by targeted next-generation sequencing

Nga wan Rachel Tam - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Evaluation of soluble FLT3 ligand as a marker of bone marrow stress and recovery

Christine Sastri - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Optimized 7-Plex cell-free DNA assay for clinically relevant KRAS mutations in colorectal cancer

Rajeswari Avula - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Post-surgical resection monitoring in early stage colorectal carcinoma patients using a circulating cell-free DNA assay with ultra-high accuracy and specificity

Stefanie A. Mortimer - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Survivin contributes to radiation resistance in head and neck cancer through regulation of DNA damage repair

Xu Wang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

YM155

Role and regulation of Aurora A in radiation resistance mechanisms in glioblastoma

Brinda Ramasubramanian - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Alisertib

Activating mutations in EGFR abrogate hypoxia-associated radiation resistance in non-small cell lung cancer

Mohammad Saki - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Higher mutation rate is associated with more frequent expression of cancer/testis antigens in human tumors

Junping Jing - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Identification of novel cancer immunotherapy targets using Sleeping Beauty mutagenesis

Laura M. Rogers - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Identify and prioritize candidate neoantigens from cancer exome sequencing with unmatched accuracy

James White - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A novel kinase connection between oncogenic signaling and myeloid-derived suppressor cell functions in tumor evasion

Jingying Zhou - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The landscape of immunostimulatory RNA transcription

Alexander Solovyov - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

N/A

Accurately identifying expressed somatic variants for neoantigen detection and immuno-oncology

Sean M. Boyle - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Excessive HCK kinase activity in the tumor stroma promotes colorectal cancer progression

Matthias Ernst - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Evaluation of immune function in the tumor microenvironment by RNA in situ hybridization to reveal spatial information on immune cell infiltration and the expression of functional mRNA biomarkers

Ming-Xiao He - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

OX40L

Analysis of genetic alternations in multiple tissue specimens from each patient: Implications for field-effect colon cancerization

Chansu Lee - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

TP53

Preclinical combination strategies to enhance the efficacy of the anti-PD-1 antibody pembrolizumab

Elaine M. Pinheiro - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Pembrolizumab

Protein phosphatase 1 regulatory subunit 1A (PPP1R1A) promotes tumor growth and metastasis via inhibition of protein phosphatase 1 in Ewing sarcoma

Wen Luo - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

N/A

Characterization of myeloid cells in bladder cancer

Neelam Mukherjee - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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