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544 : Protein phosphatase 1 regulatory subunit 1A (PPP1R1A) promotes tumor growth and metastasis via inhibition of protein phosphatase 1 in Ewing sarcoma

Researchers

Presenter

  • Wen Luo

Principal Investigators

  • Changxin Xu

  • Janet Ayello

  • Filemon Dela Cruz

  • Jeremy Rosenblum

  • Stephen Lessnick

  • Mitchell S. Cairo

Medical Centers

  • New York Medical College, Valhalla, NY

  • University of Utah, Salt Lake City, UT

  • Columbia University, New York, NY

  • Nationwide Children's Hospital, Columbus, OH

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Musculoskeletal

Disease

  • Lung Cancer

  • Ewing's sarcoma

  • Sarcoma

  • Solid malignancies

  • Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis

Biomarkers

  • Nucleoside diphosphate kinase A

  • Cyclic AMP-dependent protein kinase

  • EWS RNA Binding Protein 1

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A