App-Quantinova.ai

Stromal autophagy is required for the growth of cutaneous melanoma

Ran Ellen Zhang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Atorvastatin

Tumor associated macrophages mediates the oncogenic effect of FGF18 in ovarian cancer

Wei Wei - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Sprifermin

Mammary fibroblasts exert divergent effects on the survival of invasive breast cancer cells

Kimberly Hagel - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Adipocytes-mediated autophagy activation and metabolic reprogramming promotes colon cancer survival

Yang-an Wen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Thyroid tumor microenvironment: mutual interaction between cancer and inflammatory cells

Neha Yashpal Tuli - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

TPC-1

Metabolic and microenvironment changes in the mammary of calorie restricted, normal weight, and obese mice throughout the lifespan

Laura A. Smith - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Sulfasalazine

Significance of glypican-1 expression on tumor stromal cells in gastric carcinoma

Yuichiro Miki - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

SPARC expression stimulates paracrine inhibitory response from bone marrow stroma during dormancy of prostate cancer in the bone

Sambad Sharma - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

noggin

Stromalcell suppression of estrogen receptor in growth-arrested breast cancer cellsand promotion of outgrowth of estrogen-independent clones

Richard Steinman - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Fulvestrant

Stromal cell-induced alterations in the response of colorectal cancer cell to demethylating agents

Viswanath Das - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Vidaza

Cancer cell-stromal cell crosstalk drives fibroblast senescence and tumor progression in large cell carcinoma of the lung in culture and in vivo

Roberto Lugo - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Characterization and validation of an implantable chronic lung imaging window

David Entenberg - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Dissecting the mechanisms of hepatocyte replacement in breast cancer liver metastases

Mark R. Nathan - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Modified RECIST for monitoring hepatocellular carcinoma with computed tomography: Inter-reader variability of the response

hubert Beaumont - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Unbiased detection of disseminated tumor cells in murine bone marrow

Kenneth C. Valkenburg - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhances aggressiveness in triple-negative breast cancers

Theresa Bonner - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Pre-metastatic niche formation in palmitic acid and Caco2 BBE secreted exosomes treated HepG2 cells by the CD98-integrin-FAK pathway

Jenniffer L M Stetler - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Gastroenterology (GU)

Solid malignancies

Palmitic acid

Blocking Ezrin can inhibit HGF/Met signaling-induced metastasis

Yanlin Yu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Methadone hydrochloride

Anti-tumor and anti-metastasis efficacy of a novel Notch inhibitor (PF-03084014) in hepatocellular carcinoma

Wu Chuanxing - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

PF-03084014

Honokiol inhibits lung cancer brain metastasis through inhibition of STAT3 signaling pathway

Yongik Lee - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Honokiol

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