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4098 : SPARC expression stimulates paracrine inhibitory response from bone marrow stroma during dormancy of prostate cancer in the bone

Researchers

Presenter

  • Sambad Sharma

Principal Investigators

  • Fei Xing

  • Kerui Wu

  • Yin Liu

  • Kounosuke Watabe

Medical Centers

  • Wake Forest School of Medicine, Winston-Salem, NC

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Urology

Disease

  • Prostate cancer

  • Bone metastases

  • Solid malignancies

Biomarkers

  • Mitogen-activated protein kinase

  • p38 Mitogen-activated protein kinases

  • Cyclin dependent kinase inhibitor 2C

  • Cyclooxygenase-2

  • DNA methyltransferase 1

  • Bone Morphogenetic Protein Receptor Type 2

Drug/Treatment

  • noggin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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