App-Quantinova.ai

Caspase-1 from MDSC promote MyD88 dependent carcinogenesis that is T-cell independent

Qi Zeng - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Mast cell-derived granzyme b contributes to resistance against anti-angiogenic therapy

Mark A. Wroblewski - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Discovery of histone demethylase KDM5C inactivation as a novel mechanism for tumors resistant to VEGF RTKi via genome-wide in-vivo RNAi

Azadeh Fahim Golestaneh - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Sunitinib

Highly potent monoclonal and bispecific anti-angiogenic antibodies to VEGF and angiopoietin-2

Hangil Park - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Bevacizumab

The impact of dual targeting VEGFR2 and Tie-2 on angiogenesis using in vitro model

Khalid Alhazzani - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

L-Tyrosine

Lenvatinib in combination with everolimus demonstrated enhanced antiangiogenesis and antitumor activity in human RCC xenograft models

Yusuke Adachi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Everolimus

Antitumor activity of a combination of lenvatinib mesilate, ifosfamide, and etoposide against human pediatric osteosarcoma cell lines

Masahiro Matsuki - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Ifosfamide

The efficiency of anti-tumor effect of metformin for gemcitabine-resistant pancreatic adenocarcinoma

Keiichi Suzuki - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Gemcitabine

The tissue and cellular destination of therapeutic IgGs in glioblastoma

Gaelle Muller-Greven - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Bevacizumab

Prion-like protein Doppel is a selective therapeutic target for tumoral angiogenesis

Taslim Al-Hilal - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Targeting mir101/ EZH2/NFkb axis by FGFR1 inhibitor in mantle cell lymphoma

Lalit Sehgal - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

EZH2

The chemokine receptor CXCR4 and the cannabinoid receptor CB2R form heterodimers in non-Hodgkin lymphoma (NHL) and solid tumors leading to functional crosstalk

Martina Guerrero - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Treponema denticola, a periodontal pathogen, promotes stemness and migration in oral squamous cell carcinoma

Pachiyappan Kamarajan - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Altered mucus composition and bacterial dysbiosis promote development of colitis following chronic Notch inhibition

Ishfaq Ahmed - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Bacterial DNA integrations in the genomes of gastric tumor and adjacent samples

Kelly Robinson - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Breast cancer subtypes have distinct microbial and immune cytolytic transcriptomic signatures

Chandra Sekhar Pedamallu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

High incidence of MAC387 positive cells in the carcinoma tissues of inflammatory breast cancer patients correlate with the detection of multiple human Cytomegalovirus genotypes and invasive properties of the disease

Hossam Taha Mohamed - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Novel small molecule ONC201 induces cell death and targets chemotherapy-resistant cancer stem-like cells in triple negative breast cancer

Marie D. Baumeister - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Paclitaxel

Riboflavin targets autofluorescent-positive breast cancer stem cells upon light exposure

Shamileh Fouladdel - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Ribo-100

Exploring the utility of natural and synthetic resveratrol derivatives for bone regrowth following loss due to breast cancer therapies

Evan Robert - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Pterostilbene

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