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Kruppel-like factor 8 activates the transcription of C-X-C cytokine receptor type 4 to promote breast cancer cell invasion, transendothelial migration and metastasis

Debarati Mukherjee - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

CXCL12

Kinase-independent function of focal adhesion kinase in lung metastasis of breast cancer

Ming Luo - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

DE-074

Dysregulation of Hippo pathway in metastatic prostate cancer

Jen-Ming Huang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Vasodilator-stimulated phosphoprotein promotes 1-integrin-FAK-YAP1/TAZ signaling axis that is required for liver metastasis of GI cancer

Xiaoyu Xiang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Gastroenterology (GU)

Solid malignancies

N/A

22(S)-Hydroxycholesterol, an antagonist of LXR, inhibits breast cancer cell migration

Sewon Hwang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

LXR ligand

Hypoxia-induced WSB1 promotes the metastatic potential of osteosarcoma cells

Yijie Wang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Calponin-3, acidic (CNN3) mediates EMT-related genes in human colorectal cancer metastasis

Soon-Chan Kim - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

p53 family and oncogenic signaling in cancer metastasis

Zhi-Xiong Xiao - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Radiation response genome-wide analysis using paired pre and post-radiation FFPE human breast tumor samples

Sharareh Siamakpour-Reihani - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

N/A

Ionizing radiation switches the function of tumor-derived exosomes from messengers of tolerance to inducers of antitumor immunity

Julie M. Diamond - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Deadly fuel: Fibroblasts mediate cancer cell death through tunneling nanotubes in response to ionizing radiation

Katharina Rock - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Overexpression of hepatoma upregulated protein (HURP) promotes radioresistance in prostate cancer cells

Mohamed Hassan - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Solid malignancies

N/A

P16INK4a over-expression sensitizes HPV(-) HNSCC to radiation through down-regulation of USP7

David Molkentine - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

M3814, a novel investigational DNA-PK inhibitor: enhancing the effect of fractionated radiotherapy leading to complete regression of tumors in mice

Frank T. Zenke - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

M3814

TRIP12 as a mediator of human papillomavirus/p16-related radiation enhancement effects

Li Wang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Alpha-tocopheryloxyacetic acid (aTEA) induced immune activation synergizes with radiation therapy to treat primary and metastatic murine mammary carcinoma

Joshua M. Walker - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Piperlongumine (PPLGM) has potent tumor-radiosensitizing properties in a mouse model of lung cancer

Anastasia Velalopoulou - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A novel method to identify radiosensitizers targeting hypoxic cancer cells by high-throughput screening

Keisuke Tamari - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Optical metabolic imaging of response to radiation in radiation-sensitive and resistant lung cancer cells

Kinan Alhallak - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Nicotinamide

Tripartite motif containing 28 (TRIM28) promotes breast cancer metastasis by stabilizing TWIST1 protein

Chunli Wei - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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