App-Quantinova.ai

Clinical significance of ZNF185 intracellular localization in pancreatic ductal carcinoma

Daisuke Furukawa - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Overexpression of Rab11 and E-cadherin promotes collective cell migration and indicates a poor prognosis in colorectal carcinoma

Yuan-Chiang Chung - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Metastasis blood test by in vivo tumorsphere detection

Viktoria Denes - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Circulating tumor cells from a syngeneic mouse model of hepatocellular carcinoma demonstrate epithelial-mesenchymal transition, decreased MHC I expression, and increased CCR7 expression

Jeannette A. Huaman - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

DE-074

Re-isolated metastatic pancreatic cancer cells show distinct modulation of gene expression during liver colonization

Khamael M K Al-Taee - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Nucleotide excision repair gene expression in childhood acute lymphocytic leukemia is a predictor of early relapse

Omar Ibrahim - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Gastroenterology (GU)

Solid malignancies

N/A

Myeloid derived suppressor cells-mediated inflammation in metastasis and cancer cachexia

Maria Ouzounova - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Solid malignancies

N/A

MDSC mediated spatiotemporal tumor plasticity in breast cancer metastasis

Hasan Korkaya - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

GM-CSF

Tumor-associated osteoblasts are major mediators in facilitating bone metastatic breast cancer cell quiescence

Karen M. Bussard - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Correlation of FAP(fibroblast activation protein)-expressing cancer associated fibroblasts (CAFs) and tumor metastasis in esophageal carcinoma

Hajime Kashima - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Reactive endosteum in prostate cancer bone metastases: role of tenascin-C in regulating cancer cell adhesion and proliferation

Rebeca San Martin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Cthrc1 mediated by myeloid-specific TGF- signaling stimulates NSCLC bone metastasis

Paul G. Daft - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Prostate cancer-derived exosomes alter the metabolic microenvironment of bone marrow pre-metastatic niche through PKM2 to promote bone metastasis

Jinlu Dai - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The role of CCL2 CCL17 CCL22-CCR4 axis in prostate cancer metastasis

Aerken Maolake - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

IL6 mediated inflammatory loop reprograms normal to highly metastatic cancer stem cells at pre-HCC liver in 2SP+/- mice

Abhisek Mitra - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Defective collagen production by mammary epithelia leads to increased breast cancer metastasis: a novel role of vacuolar ATPase

Gajendra K. Katara - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

PTEN is an important mediator of tumor and glia cell crosstalk in breast cancer brain metastasis

Harriet Wikman - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

GM-CSF

The progesterone analogue, Norgestrel, impairs tumor immunity and promotes metastatic breast cancer progression

Tomas Dalotto Moreno - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Norgestrel

Neuropilin 2 regulates lung disseminated tumor cell escape from dormancy and progression into metastasis

Paloma Bragado Domingo - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Neuropeptides

Intratumoral injection of interleukin-17 inhibits distant metastasis of radiation-induced recurrent tumor

Yi-Nan Li - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Interleukin

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