App-Quantinova.ai

Local and sustained delivery of tamoxifen for the prevention of ER+ breast cancer using a nanochannel delivery platform

Carly S. Filgueira - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Raloxifene

IT-147: A stabilized polymer micelle formulation of epothilone D for treatment of solid tumors

Adam Carie - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

EpoD

Oral delivery of drug-loaded microspheres for cancer

Duc P. Do - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Vorinostat

Dual antibody gold nanoconjugate significantly enhances cytotoxicity in metastatic breast cancer

Ajit Zambre - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

P32-targeting TT1 peptide delivers nanoparticles to intracranial glioblastomas

Pille Saalik - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A novel bicistronic reporter-based high-throughput screening platform for discovery of transcription-targeted lead compounds

Liwei Lang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Systematic deconvolution of kinase inhibitor profiles identifies synthetic lethal targets in ERBB2-mutant and BRD4-NUT rearranged cancer

Johannes Braegelmann - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Methadone hydrochloride

New NCI experimental therapeutics program (NExT) small molecule libraries for academic investigator hts projects

Raj N. Misra - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Developing 384-well and 1536-well cell growth inhibition assay workflow for screening drug-drug combination in tumor cell lines

Yvonne Li - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

DMSO

Structure-based drug design of 3-site binding, high affinity inhibitors of S100B in malignant melanoma

Michael C. Cavalier - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Novel proton coupled folate transporter (PCFT) and reduced folate carrier (RFC) pharmacophore models for development of transporter-selective antifolates

Sudhir Raghavan - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Methotrexate

Novel 4-(pyrimidin-2-yl)morpholines targeting the colchicine-binding site of tubulin

Alexander M. Sele - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Colchicine

IHC and RT-PCR assays for detection of cancer antigen NY-ESO-1 in human tissues

Abdel Halim - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

HT-1080

Impact of biospecimen pre-analytical factors on molecular analysis

Rachana Agarwal - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Solid malignancies

N/A

Identification of the functional significance of mutations using the novel precision cancer analysis system

Gabi Tarcic - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Solid malignancies

N/A

Detecting cancer mutations at the resolution of individual DNA molecules for longitudinal monitoring

Christina M. Wood - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

NGS-based CNV detection sensitivity is dependent upon nucleic acid input quality

Josh Haimes - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A complete workflow for high-throughput isolation and analysis of cell-free DNA from urine

Alex J. Rai - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A comprehensive gene panel for precise diagnosis and treatment of childhood cancer

Timothy J. Triche - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Clinical research results for a NGS-based kit for targeted detection of clinically relevant gene rearrangements in lung tumor samples

Jeoffrey J. Schageman - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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