App-Quantinova.ai

Novel adjuvants in triple negative breast cancer chemotherapy

Antonio Rampoldi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The amino acid transporter SNAT4: Potential role as a tumor suppressor in melanoma

Nicholas J. Otte - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Glutamine

Leptin-induced NILCO in endometrial cancer is linked to obesity

Danielle Daley-Brown - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Evaluation of small-molecule FASN inhibitors in preclinical models of colorectal cancer

Yekaterina Y. Zaytseva - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

TVB2640

Quantification of NADPH balance in cancer

Ling Liu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

folitixorin calcium

The anti-Warburg agent BPM 31510 arbitrates fatty acid metabolism in eliciting an anticancer response

Bianca Jambhekar - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Trimetazidine

Repurposing the FDA-approved drug carbidopa to treat human cancers

Vadivel Ganapathy - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Norepinephrine bitartrate

Structural features of novel dimeric quinacrines that have single-agent antitumor activity determine the mechanism of action: destabilization of mTORC1/lysosomal interaction versus DNA damage

Vito W. Rebecca - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Hydroxychloroquine

Functional genomics reveals dependency on 6-phosphogluconate dehydrogenase in OXPHOS-deficient tumors

Yuting Sun - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

N/A

A prolyl-hydroxylase inhibitor, ethyl-3,4-dihydroxybenzoate, induces cell autophagy and apoptosis in esophageal squamous cell carcinoma cells

Wei Li - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

PEG-LPrA2 is a non-toxic adjuvant for triple negative breast cancer

Courtney D. Dill - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Autophagy as a mediator of increased mammary cancer risk in socially isolated mice

Leena A. Hilakivi-Clarke - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Solid malignancies

Medroxyprogesterone

A mouse model of allelic loss of the core autophagy gene BECN1 in ovarian cancer

Joe R. Delaney - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Targeting tumor-stroma metabolic symbiosis for head and neck cancer therapy

Dhruv Kumar - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Crizotinib

Fumarate hydratase deficiency redirects glucose metabolism of hypoxic cancer cells into the pentose phosphate pathway

Luana Schito - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

N/A

Characterizing the metabolic dependencies of rhabdomyosarcoma and Ewing's sarcoma cells

Sameer Issaq - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Glutamine

Leptin induces early onset and aggressiveness of pancreatic cancer

Adriana Harbuzariu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Cellular phenotypes of a novel series of 3-phosphoglycerate dehydrogenase inhibitors

Nello Mainolfi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Nicotinamide

Metabolic hormones FGF19/15 promote hepatocellular carcinoma through activation of CSCs in fatty liver

Guozhen Cui - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Gastroenterology (GU)

Solid malignancies

N/A

Glutamine drives glutathione synthesis and contributes to radiation sensitivity of A549 and H460 lung cancer cell lines

Daniel Sappington - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

glutathione

Filters

41730 Abstracts