App-Quantinova.ai

Modeling the rise of intratumoral heterogeneity in growing, static, and regressing human colorectal polyps

Chelsie K. Sievers - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

TP53

The analysis of the genomic evolution of squamous cell carcinoma of the lung

Arthur Krause - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Single-cell DNA sequencing identifies a late dissemination model in metastatic colorectal cancer

Marco L. Leung - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Identification of the carcinoma and immune cells in the breast cancer by single-cell RNA sequencing

Woosung Chung - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Genetic difference between multicentric carcinogenesis and intrahepatic metastasis of hepatocellular carcinoma

Yutaka Midorikawa - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Clonal evolution in noncancerous esophageal mucosa in normal and cancer-bearing individuals

Akira Yokoyama - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Single-cell transcriptome analysis guides tailored combinatorial therapeutics in refractory kidney cancer

Kyu-Tae Kim - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Comparative genomic analyses of synchronous colorectal cancers by exome sequencing

Ulrika A. Hanninen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Managing metastatic breast cancer via serial monitoring with circulating cell-free tumor DNA next generation sequencing testing

Laura Austin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Isolation of primary human tumor cells significantly reduces bias in molecular analysis and improves culture of target cells

Lena Willnow - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Development of 1- and 3-phosphohistidine monoclonal antibodies utilized as novel tools to study histidine phosphorylation

Wayne A. Speckmann - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

L-Tyrosine

Atypical protein kinase C inhibition in prostate cancer cells: a study of ICA-1 and ACPD

Andre H. Apostolatos - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

ICA-1

ASN0007, a potent ERK1/2 inhibitor with strong antitumor activity in multiple RAS mutant models

Sanjeeva P. Reddy - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Ravoxertinib

Mechanism of CDKN3 overexpression in cancer

Chao Fan - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

L-Tyrosine

LMTK3 is a novel regulator of oncogenic KIT in KIT-mutant cancers

Lillian R. Klug - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

L-Tyrosine

Increased PKR expression inhibits differentiation of hematopoietic stem cells

Richard L. Bennett - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Defining the role of PAK7 variants in melanoma

Kyle M. LaPak - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Analysis of resistance to RTK inhibitors using a novel RTK multiplex assay

Lu Chen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

L-Tyrosine

Regulation of mitochondrial biogenesis in primary human clear cell renal cell carcinoma cells

Helen A. Nilsson - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

BPM 31510-induced alteration in Complex II activity is functionally linked to cell death activation pathway in a preclinical model of triple-negative breast cancer

Tulin Dadali - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

atpenin A5

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