App-Quantinova.ai

PTEN expression, cholesterol metabolism, and lethal prostate cancer

Konrad H. Stopsack - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25A

Yuanzhong Wu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A transposon-based forward genetic screen for steatosis-associated liver cancer drivers

Barbara R. Tschida - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Dopamine hydrochloride

In vivo pooled shRNA library screens identify cancer genes driving epithelial ovarian cancer

Michiko Kodama - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Cas9 protein engineering for cell cycle-specific genome editing to enhance homology directed repair

Tony Gutschner - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

CellMiner, a systems pharmacological web-application for the NCI-60 cancerous cell-lines: Updates, data integration, and translationally relevant results

William C. Reinhold - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Tamsulosin Hydrochloride

KPNA7 nuclear import protein - a critical regulator of cancer cell growth

Elisa M. Vuorinen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Establishment of lung cancer patient derived xenograft model from circulating tumor cells: Identification of somatic mutations associated with metastatic potentials

Chansu Lee - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Erlotinib hydrochloride

RNA-seq, exome-seq, functional RNAi screening and bioinformatics analyses identify molecules promoting aberrant activation of classical and alternative NF-kB pathways in head and neck cell lines

Hui Cheng - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A discovery on splicing variant patterns of leucine-tRNA synthetase gene based on targeted RNA sequencing

Hyo Jin Song - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

Rapacan

Functional effects of MutL homolog 1 promoter polymorphism in prostate cancer

Shinichiro Fukuhara - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Recurrent KRAS G12V pathogenic mutation in adenomatoid odontogenic tumors

Carolina C. Gomes - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The mutational landscape of mucinous carcinomas of the breast

Salvatore Piscuoglio - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Integrated analysis of copy number, sequence variant and gene expression data in kidney chromophobe cohort

Andrea J. OHara - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Somatic mutations and copy number variations in cancer-associated genes in 695 ovarian cancer patients

Elizabeth H. Stover - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Targeted sequencing from endoscopic ultrasound-guided fine needle aspirates of pancreatic ductal adenocarcinoma

Joo Kyung Park - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

TP53

A novel PTPRK-FILIP1 fusion gene in invasive mucinous adenocarcinoma of lung without known driver mutations

Sung-Hye Hong - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

SLC34A2

The landscape of somatic genetic alterations in BRCA1 and BRCA2 breast cancers

FC Geyer - San Antonio Breast Cancer Symposium (SABCS) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

TP53

Pan-cancer analysis of sex differences in somatic mutation profiles

Constance H. Li - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Transcriptionnal profiling of upper-tumor urothelial carcinomas

Gabriel Malouf - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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