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41730 Abstracts

EMT in cancer cells promotes the extracellular matrix remodeling by cancer-associated fibroblasts

Shinya Neri - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Becaplermin

Extracellular Survivin uptake by cancer cells via receptor-mediated endocytosis

Amber Gonda - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

11 is pro-proliferative and promigratory integrin and its expression is upregulated by the MYC oncogenic factor in colorectal cancer

Salah Boudjadi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

CD151-31 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion

Pengcheng Zhou - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Acid-induced collagen remodeling promotes cancer progress as a result of niche engineering competition between cancer and stroma cells

Mehdi Damaghi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Hic-5 modulation of the stromal matrix is required for mammary tumor progression

Gregory J. Goreczny - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Development of a decellularized tumor model for the evaluation of breast carcinomas

Elizabeth Martin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

DE-074

Interplay between ECM stiffness, miR-203 and mammographic density

Ivory Dean - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Tumor-secreted acids alter macrophage phenotype

Asmaa El-Kenawi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

sodium bicarbonate

Unexpected roles for stromal MMP3 during breast cancer

Emilia Hartland - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The involvement of connective tissue growth factor in nonalcoholic steatohepatitis and liver cancer development under diabetic condition

Liya Pi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Gastroenterology (GU)

Solid malignancies

N/A

MDM2 regulates intracellular pathways in TNBC and osteosarcoma that affect osteoclastogenesis

David J. Olivos - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The role of microvesicles on immune function in response to cancer

Ritu Jaiswal - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Pre-clinical development of next generation inhibitors of the enzymes indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase as cancer immunotherapies

Alan Wise - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

tryptophan

Complex, 3D tissues for modeling the immune response in cancer and predicting the activity of immunotherapies

Tessa M. Des Rochers - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Immunomodulating cytokine profiling of docetaxel-treated human prostate cancer specimens

Debapriya G. Mehrotra - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Docetaxel

Immunomodulatory activity of bitter melon extract in head and neck squamous cell carcinoma

Sourav Bhattacharya - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The link between therapy-induced senescence and anti-tumor immune microenvironment in melanoma

Anna E. Vilgelm - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Clinical verification of antitumor autoimmune response in eribulin chemotherapy for breast cancer

Wataru Goto - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Eribulin

Characterization of tumor immune microenvironment in response to PD-L1 therapy initiated at different time points post inoculation in syngeneic mouse models

Geeta Sharma - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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