App-Quantinova.ai

The BET inhibitor INCB054329 enhances the activity of checkpoint modulation in syngeneic tumor models

Holly K. Koblish - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

epacadostat

Effects of MAPK pathway inhibitors in the tumor immune microenvironment

Marcia P. Belvin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Epigenetic treatment of ovarian cancer cells increases immune cell recruitment to the tumor microenvironment: implications for response to immune checkpoint therapy

Meredith L. Stone - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Vidaza

Cancer immunotherapy with immunomodulatory anti-CD137 and anti-PD-1 monoclonal antibodies requires Batf3-dependent dendritic cells

Alfonso R. Sanchez-Paulete - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Poly-ICLC

SOCS-1 inhibits tumor growth by enhancing T cell mediated antitumor immunity related to PD-L1

Satoshi Nakagawa - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Engineering dendritic cell-based vaccines as targeted immunotherapy against medulloblastoma, neuroblastoma, and Ewing sarcoma

Stacey Zahler - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Interferon

Evaluation of the immune response following treatment with anti-CTLA-4 antibody, radiation therapy or the combination in a murine model of breast cancer

Maryland R. Franklin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Emerging prognostic biomarkers in colorectal cancer: HURP and ZEB1

Logan Fair - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Chronic diseases and age >65 years may cause false positive results in colorectal cancer screening with the blood-based Sept9 methylation assay

Mai-Britt W. rntoft - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

UbcH10 may represent a potential marker of gastric carcinoma

Mengxuan Yang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Cisplatin

In Situ analysis of FGFR2 RNA and comparison with FGFR2 gene copy number by dual-color in situ hybridization in a large cohort of gastric cancer patients

Yasutoshi Kuboki - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Solid malignancies

L-Tyrosine

Detection of HBV-host junction DNA sequences in urine of patients with hepatocellular carcinoma

Selena Lin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Targeted proteomic analysis of hepatocellular carcinoma and its histologic mimickers

Fabiola Cecchi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The function role of Brf1 in alcohol-induced human and mouse hepatocellular carcinoma*

Shuping Zhong - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Evaluating a novel biomarkers set for postoperative outcome in patients with gastrointestinal cancer

Kunizaki Masaki - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Use of whole slide digital image analysis for determination of expression of Twist-1 in normal panceata and stage IV pancreatic ductal adenocarcinomas

Max Jacobsen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Overexpression of Reg proteins in human pancreatic ductal adenocarcinoma and acinar-to-ductal metaplasia

Qing Li - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Detection of functional P-selectin ligands expressed on colon cancer tissue using a novel flow-based assay

Eric W. Martin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Keratin 13 drives the dissemination of bone and brain metastases of human prostate and breast cancer cells

Lijuan Yin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A distinct AMP-activated protein kinase phosphorylation site is associated with metastasis and castration-resistance in prostate cancer

Melissa A. Babcook - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Androgen Tear

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