App-Quantinova.ai

Discovery and characterization of two novel drivers of hepatocellular carcinoma

Charlotte R. Feddersen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-sequencing

Benjamin Izar - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

High-throughput in vivo systems biology using implantable microdevices

Oliver Jonas - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Selective cross-cohort discovery of transcriptional mechanisms presiding over high-risk neuroblastoma subtype state maintenance

Presha Rajbhandari - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Live-imaging the interface between homeostasis and cancer initiation

Cristiana Pineda - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

CETSA as a new strategy to understand efficacy, adverse effects and resistance development of anticancer drugs

Par Nordlund - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Tissue stiffness and hypoxia regulate breast cancer stem cells through ILK

Mei-Fong Pang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Mesenchymal stem cell-derived collagen I plays a role in organizing breast cancer cell migration and metastasis

Maria E. Gonzalez - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Impact of Interleukin-22 on K-ras mutant lung tumor microenvironment and stemness properties

Nasim Khosravi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Interleukin

SMYD2-mediated lysine methylation regulates nuclear transport of beta-catenin in human cancer cells

Xiaolan Deng - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Mutant ABL1 is a genetic dependency in non-small cell lung cancer amenable to pharmacological intervention

PEDRO Torres-Ayuso - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Imatinib

ZEB2 drives cell motility and metastasis in ER+ breast cancer cells through a novel, E-cadherin independent pathway

Hope E. Burks - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

c-Myc-driven lymphomas require calcium-modulating cyclophilin ligand (CAML) for survival and proliferation

Jennifer C. Shing - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Tamoxifen

CPAP contributes to HCC malignancy through regulating inflammatory pathways

Liang-Yi Hung - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Identification and characterization of patient-derived PREX2 mutation in HCC

Yen-Fu A. Chen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Phosphatidylinositol

Exploration of alternative pathways mediated by IFNL4 and related to cell proliferation and death in a hepatoma cell line

Fang Wang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

IFN-lambda

Heparan sulfate proteoglycans mediate SW13 oncogenic potential and response to granulin

McKale Davis - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Molecular features of hepatocellular carcinoma arising from non-alcoholic fatty liver

Makoto Takeda - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Methylation and acetylation are novel post-translational modifications identified for the pre-apoptotic protein kinase C (PKC) delta

Noemi Kedei - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

bryostatin-1

Comprehensive study of TGF- pathway-driven functional molecular characterization of human hepatocellular cancer

Jian Chen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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