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41730 Abstracts

Role of calreticulin in the spontaneous development of lung adenocarcinoma: Evidence from a novel transgenic mouse model

Nasrin Mesaeli - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Uteroglobin

Mig-6 ablation cooperates with oncogenic Kras in promoting mouse lung tumorigenesis

Jian Liu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Systematic in vivo analysis of PI3K pathway aberrations in a mouse model of invasive lobular carcinoma

Martine Van Miltenburg - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

AZD-8055

Lipid metabolism-independent role of apolipoprotein (E) levels in colon carcinogenesis through a regulating inflammation and active -catenin

Abdelmetalab F. Tarhuni - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

ICAM-1

A role for RAD52 as a lung cancer susceptibility gene in the 12p13.33 locus

Rachel Lieberman - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The oncopig cancer model as a validated model for human hepatocellular carcinoma

Kwame A. Darfour-Oduro - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Alfa-fetoprotein

Leptin mediates the anti-breast cancer effects of environmental enrichment

Grant Foglesong - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Dynamic visualization of cancer cell engraftment into immune compromised zebrafish

John C. Moore - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Interleukin

Pigs as a new weapon against cancer: Modeling solid tumors in porcine

Andrew Diaz - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Pre-clinical study using KRAS mutant mouse models for lung cancer immunotherapy together with MEK inhibition

Jiehui Deng - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

RNAi and CRISPR/Cas9 based in vivo models for drug discovery

Prem K. Premsrirut - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Doxycycline

Cancer drugs on the fly: whole-animal chemical screening in Drosophila identifies unexpected role for EGFR in RAF intestinal stem cell tumors

Michele Markstein - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

The association between gastric Mucin 5AC (MUC5AC) expressions, transforming growth factor- (TGF-) signal, and histopathological phenotypes of lung cancer in xenograft models

Ryo Sato - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Reporter systems to measure dynamics and specificity of targeted cancer therapy

Rebecca T. Marquez - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Methadone hydrochloride

Assessment of novel benzosuberene-based vascular disrupting agents (VDA) on diverse tumor lines

Li Liu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

NSC-348103

Combined contrast enhanced ultrasound and photoacoustic imaging reveals both functional flow patterns and dysfunctional vascular pooling in tumor models

Melissa Yin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Peptide probes binding to radiation-inducible cell surface GRP78 as a novel targeting strategy for various tumors

Vaishali Kapoor - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A dual-motif CAIX inhibitor, [64Cu]XYIMSR-06, for PET imaging of clear cell renal cell carcinoma

IL MINN - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

microPET/CT imaging of the mobilization of CD11b+ cells

Qizhen Cao - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Targeting GPNMB with 89Zr-CR011 for PET imaging of triple negative breast cancer

Bernadette V. Marquez - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

glembatumumab

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