App-Quantinova.ai

Feasibility and efficacy of a precision treatment approach for triple-negative breast cancer in mouse models

Hui Liu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Methadone hydrochloride

Peptidomimetic Src kinase inhibitor KX-01 sensitizes estrogen receptor -negative breast tumor xenografts to tamoxifen by inducing ER re-expression

Murali Anbalagan - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Alora

The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRASQ61K melanoma

Cynthia M. Simbulan-Rosenthal - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Mebendazole

Ruxolitinib inhibits STAT-3 activation in glioblastoma

Samuel Fehling - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Ruxolitinib phosphate

SLFN11 is a biomarker of sensitivity to PARP inhibition and chemotherapy in small cell lung cancer (SCLC)

C. Allison Stewart - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Irinotecan

Simultaneous absolute quantitation of ATP-binding cassette transporters in canine tissues via targeted proteomics

Luke A. Wittenburg - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Trypsin

Mass spectrometry imaging determines biomarkers of early adaptive precision drug resistance in lung cancer

Erin H. Seeley - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

TAE684

Proteome-wide approach to identify novel biomarkers in oral tumorigenesis

Sivagnanam Ananthi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Proteomic approach to identify biomarkers for invasive cervix cancer: a prospective pilot study

David P. Mysona - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Comprehensive delineation of stromal proteins implicated in the multistage carcinogenesis and identification of Tenascin-C as stromal marker for metastasis of colon carcinoma

Yongheng Chen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Quantitative human secretome: a technology to measure the expression levels of thousand of secreted proteins

Ruo-Pan Huang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Breast cancer proteogenomics landscape defines subtype specific protein level regulations and reveals proteins coded by pseudogenic loci

Henrik Johansson - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Patient-specific druggable networks in lethal prostate cancer through proteome-guided multi-omic integration

Justin M. Drake - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Androgen Tear

An aptamer-based multiplexed proteomic technology reveals differential PKC ligand responses

Jinqiu Chen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

bryostatin-1

NCI's Clinical Proteomic Tumor Analysis Consortium

Mehdi Mesri - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Solid malignancies

N/A

Development of quantitative methods for assessing metastatic potential of human primary tumors

Kelly A. Martin - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Unique pleural vs peritoneal mesothelioma exosomal signature: does mesothelial cell susceptibility to asbestos matter

Arti Shukla - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A xenograft mouse model coupled with in-depth cell surface proteome analysis facilitates further elucidation of K-Ras driven tumorigenesis in lung carcinoma

Xiaoying Ye - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Novel in vivo pan-Hsp90 family protein inhibitor, Panvotinib-401, showed potent anticancer activities without HSF1 activation

Byoung Heon Kang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Optimizing the antitumor efficacy of AuNR-assisted plasmonic photothermal therapy and its molecular impact

Mohammad Aminur Rahman - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

rifampicin

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