App-Quantinova.ai

Targeted therapy of leukemia and Ewing's sarcoma by human antibody-targeted nanoparticles

Hyunggyoo Kang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Doxorubicin

A cancer treatment based on synergy between anti-angiogenic and immune cell therapies

Luis F. Soto-Ortiz - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Bevacizumab

Transcriptome analyses reveal fusion transcripts and transcript variants that are recurrent across sample series of testicular germ cell tumors

Andreas M. Hoff - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Combining whole-exome and RNA-Seq data improves the quality of PDX mutation profiles

Manuel Landesfeind - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Radiotherapy and immunotherapy in cancer: A mathematical model

Raphael Serre - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A computational algorithm to predict tumor growth and cancer stem cell proportion in-vitro and in-vivo from single-cell observations

Alexander T. Pearson - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

EGFL6

Development of an individualized 3D transport model of topotecan for a patient-derived orthotopic xenograft model of pediatric neuroblastoma

Abbas Shirinifard - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Topotecan Hydrochloride

Model evolution technique as a novel concept for characterization of tumor heterogeneity in dynamic contrast enhanced MRI studies

Hassan Bagher-Ebadian - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Spatiotemporal progression patterns in metastatic lung cancer treated with bevacizumab

Jeremy M. Mason - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Bevacizumab

Joint somatic mutation and germline variant identification and scoring from tumor molecular profiling and ct-DNA monitoring of cancer patients by high-throughput sequencing

Francisco M. De La Vega - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Inhibition of human telomerase by new purine analogs

Wilnelly M. Hernandez-Sanchez - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Zidovudine

Cell cycle regulated mitophagy: a key step at the G1/S metabolic checkpoint

Daniela Annibali - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Glutamine

Lipid mediated nutrients sensing checkpoint in G1 phase of the cell cycle

Deven Patel - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Glutamine

Reintroduction of DAXX suppresses alternative lengthening of telomeres in osteosarcoma

Kathryn E. Driest - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

N/A

Association of TERT promoter mutations with telomerase expression in melanoma

Seungjae Lee - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Novel function of the RAI2 protein in genomic integrity of breast cancer cells

Stefan Werner - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Quantitative assessment of chromosome instability induced through chemical disruption of mitotic progression

Sarine Markossian - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Mechanistic basis of Palbociclib combinatorial activity in ER+ breast cancer and non-breast indications

Stephen Dann - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Palbociclib

A novel branched DNA-based multiplex method for telomere analysis at the single-cell level by flow cytometry

Steve Lai - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

USP37 promote oncogenesis by stabilizing protein involved in DNA damage repair pathway and provides a novel way to modulate Chk1 activity

mayank singh - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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