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41730 Abstracts

Assessing the efficacy of the anti metabolic drug, CPI-613, for targeting of ovarian cancer stem cells

Chiara Bellio - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Olaparib

Citral reduces breast tumor growth by inhibiting cancer stem cell marker ALDH1A3

Margaret L. Thomas - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A red-shifted fluorescent substrate for aldehyde dehydrogenase, AldeRed 588-A, for labeling viable ALDH-positive cells

Nick Asbrock - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Iron control is a novel therapeutic target of cancer stem cells

Toshiaki Ohara - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Deferoxamine

Second generation HDAC inhibitor, Quisinostat reinstates RD3 in neuroblastoma CSCs and promotes stem cell differentiation

DINESH BABU SOMASUNDARAM - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

quisinostat

Ewing sarcoma associated long non-coding RNA determines neural cell fate of the tumors

Sheetal A. Mitra - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

stannous fluoride

Crosstalk between stem and non-stem cells in glioblastoma promotes radioresistance in a CD109-dependent manner

Mutsuko Minata - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

A novel role for brachyury as a key regulator of sonic hedgehog signaling (Shh) and maintenance of stemness in gliomas

Divya Kesanakurti - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

IRS-1/LC3 nuclear structures and glioblastoma drug resistance

Adam Lassak - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Temozolomide

STAT3 is a central regulator of proliferation, invasion and metabolism in GBM tumor initiating cells

Ian Restall - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Glutamine

Transcriptional profiling of glioblastoma stem-like cells reveals enrichment of ion channels with functional implications for malignancy

Julia Pollak - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

STAT3 is a key regulator of an EMT-like process mediated by Slug in GBM

Charles Chesnelong - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Regulation of angiogenic factors in glioblastoma progression

Carolina Larrain - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Heparin

MDA-9/Syntenin (SDCBP) promotes self renewal and malignancy in cancer stem cells

Sarmistha Talukdar - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Mechanism and role of SOX2 repression in human germline specification

Kushwaha Ritu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Tigason

Expression of ABCF1 with stem cell markers CD133/GEP/beta-catenin in fetal liver and liver cancer cells

Sze Wai Fung - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Adrucil injection

Live cell detection of intracellular biomarkers maintains cancer stem cells for further experimentation

Don Weldon - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Alginate-based 3D system for the enrichment and culture of cancer stem cells

Karen A. Simon - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

EpCAM-positive cancer stem cells acquired chemoresistance in hepatocellular carcinoma

Harshul Pandit - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Doxorubicin

The emerging role of SOX2 in cancer cell plasticity and EGFR-TKI resistance

Yu-Fan Chiu - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

L-Tyrosine

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