App-Quantinova.ai

Head and neck patient derived xenografts acquire histopathological and growth rate changes over increasing passages

Alexander Pearson - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

High-complexity neutral genomic barcoding technology reveals extensive clonal dynamics in multiple human cancer model systems

Allison ML Nixon - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

N/A

Understanding the dynamic interplay between genetically different cancer cell clones in glioblastoma

Min Guo - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Microfluidic single cell exome-seq and RNA-seq analysis of tumor composition

Ioannis Ragoussis - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Pan-cancer analysis of clonal evolution reveals the costs and adaptive benefits of genomic instability

Noemi Andor - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Microarray analysis of polysome-associated mRNAs from different regions of the same human glioblastoma reveals intratumoral heterogeneity

Glaucia N. Hajj - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Direct assessment of sequence heterogeneity in human cancers by Duplex Sequencing

Michael W. Schmitt - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Heterogeneity of colorectal cancers and multiple liver metastases by mutation and copy number profiling

Sharmini Alagaratnam - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

TP53

Colorectal primary tumors and metastases are highly homogeneous regarding driver mutations

Miguel Silva - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Molecular mechanisms orchestrating intratumoral heterogeneity in Kras-driven carcinomas

Roxana Azimi - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

TP53

Dysregulation of lung developmental pathways associated with LKB1 loss in lung cancer

Jacob M. Kaufman - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Melatonin action in xenograft model of breast cancer, comparing radiopharmaceuticals in the detection of intratumor heterogeneity by PET/CT confirmed by immunohistochemical markers

Andre L. Mota - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Melatonin

Inhibition of PLK1 induces growth arrest and apoptosis in tumorigenic OS cells

Maria V. Guijarro - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Cell type-specific deconvolution of heterogeneous tumor samples with immune infiltration using expression data

Zeya Wang - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

ADAR1-dependent RNA editing is a mechanism of therapeutic resistance in human plasma cell malignancies

Elisa Lazzari - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Adenosine

Important role of FTO in the survival of rare panresistant triple-negative inflammatory breast cancer cells under a severe metabolic challenge

Balraj Singh - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Glutamine

Efficiency in recovery of pure tumor cell populations from limited tumor tissue specimens intended for clinical application

Valeria Sero - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Circulating tumor cells reveal the genetic evolution of metastatic breast cancer

Simon A. Joosse - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Deep phenotyping of dissociated solid tumor cells from breast cancer specimens

Aaron J. Middlebrook - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Genome-wide mapping of MYCN, MYC, and MAX binding across neuroblastoma cell lines identifies novel transcriptional targets

Jo Lynne Harenza - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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