App-Quantinova.ai

TX1111: a peptide homologue of Topoisomerase-1 sensitizes pancreatic cancer cells to gemcitabine

Manu Gnanamony - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Gemcitabine

Acquired tamoxifen resistance sensitises breast cancer cells to bisphosphonates

Dionysia Lymperatou - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Zoledronic acid

Enhanced in vitro activity of dianhydrogalactitol (VAL-083) in combination with platinum drugs: Impact of p53 and platinum-resistance

Anne Steino - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Dianhydrogalactitol

Pharmacologic, pharmacodynamic action of MELK kinase inhibitor OTS167 in cancer cells

Suyoun Chung - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

OTS167

In vitro characterization of PTAU and FU interactions in colon cancer cells

Esther A. Suswam - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Fluorouracil

Development of radiolabelled drug carrier systems for molecularly targeted radiotherapy

Jyothi U. Menon - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Solid malignancies

Doxorubicin

Tenascin-C binding peptides for cancer targeting

Prakash Lingasamy - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Targeted delivery of chemotherapeutic agents to solid tumors via systemic Nano-diamino-tetrac

Thangirala Sudha - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Paclitaxel

Beta-hairpin peptide hydrogels as scaffolds for 3D high-throughput cancer drug discovery

Peter Worthington - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Circle Akt in: Epitope catalyzed assembly of macrocyclic therapeutics against phosphorylated Akt

Arundhati Nag - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Anemarrhena rhizome and Schisandra chinensis inhibit viability and promote apoptosis in pancreatic cancer cell lines

Catherine Mar Elia - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Adrucil injection

A novel injectable formulation of quercetin reliant on the ability of the drug to complex copper

Kent T. Chen - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

cisplatin + irinotecan

Sann-Joong-Kuey-Jian-Tang can inhibit human breast cancer cells through dural- blocking both the Ras/Raf/MEK/ERK and Ras/PI3K/Akt/mTOR pathways

CHIN CHENG SU - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Rapacan

Garcinone inhibits nasopharyngeal carcinoma cell growth and arrests cell cycle via modulating the expression of ATR/Stat3/4E-BP1

Yudui Xia - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Isolation and anticancer properties of some naturally occurring sesquiterpene lactones from Pulicaria undulate

Mohammed M. Arab - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

camptothecin

Imaging the kinetics of targeted nanoparticles to pancreatic cancer

Jonathan Moreno - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

Daunorubicin

Stabilityof injectable phospholipid nanoparticles loaded with paclitaxel: influence oflipid composition, drug concentration, storage temperature, lyophilization, andadditives

Shrada Prabhulkar - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Paclitaxel nanoformulation

New oxazaphosphorine prodrugs for immunotherapy and nanomedicine against cancer

Charles Skarbek - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Solid malignancies

Cyclophosphamide

Small molecule drug conjugates targeted to cholecystokinin 2 receptors

Jyoti Roy - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Vinblastine

Integrin v3-targeted lipase-labile docetaxel-prodrug micelles preferentially treat breast cancer bone metastases

Michael H. Ross - American Association for Cancer Research (AACR) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Docetaxel

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