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XBP1 PROMOTES PRE-B CELL ACUTE LYMPHOBLASTIC LEUKEMIA THROUGH OF IL-7 RECEPTOR SIGNALING IN MICE

Azam Salimi - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

COMBINATION OF FLOTETUZUMAB, A CD123 X CD3 BISPECIFIC DART® MOLECULE, AND BLINATUMOMAB, A CD19 X CD3 BITE MOLECULE, TO PREVENT ANTIGEN ESCAPE IN B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA

Dragana Slavkovic Lukic - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Blinatumomab

THIOREDOXIN SYSTEM INHIBITORS ARE EFFECTIVE AGAINST B CELL ACUTE LYMPHOBLASTIC LEUKEMIA IN VITRO AND IN VIVO

Klaudyna Fidyt - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

thioredoxin

FREQUENCY AND PROGNOSTIC IMPACT OF ZEB2 H1038/Q1072 MUTATIONS IN CHILDHOOD B-OTHER ACUTE LYMPHOBLASTIC LEUKEMIA

Marketa Zaliova - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

ETV6/RUNX1 FUSION GENE ABROGATION DECREASE THE ONCOGENIC POTENCIAL OF TUMORS CELLS IN A PRECLINICAL MODEL OF ACUTE LYMPHOBLASTIC LEUKEMIA

Adrian Montao - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Prednisolone

MLL-AF4 CAUSES ABERRANT UPREGULATION OF PROM1 (CD133) IN ACUTE LYMPHOBLASTIC LEUKEMIA BY CONTROLLING ENHANCER-PROMOTER INTERACTIONS

Laura Godfrey - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

CD9 IS AN ADVERSE PROGNOSTIC MARKER AND PROMISING THERAPEUTIC TARGET IN HIGH-RISK PEDIATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA

Chi Zhang - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

THE XPO1 INHIBITOR KPT-8602 WORKS SYNERGISTIC WITH DEXAMETHASONE TO INHIBIT ACUTE LYMPHOBLASTIC LEUKEMIA CELLS

Delphine Verbeke - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Glucocorticoid

THE TETRASPANIN CD9 REGULATES GLUCOCORTICOID SENSITIVITY IN PEDIATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA

Jimmy Man Hon Li - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

6-mercaptopurine

LONG-TERM INHIBITION OF CHK1/CHK2 KINASES MODIFY ACUTE LYMPHOBLASTIC LEUKEMIA CELL LINE RESPONSE TO DNA DAMAGING AGENTS

Andrea Ghelli Luserna Di Rora' - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

Methotrexate

DIFFERENTIAL EXPRESSION PATTERNS OF SPECIFIC LONG NONCODING RNAS AND COMPETING ENDOGENOUS RNA NETWORK IN ACUTE LYMPHOCYTE LEUKEMIA

Weimin Wang - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Acute lymphoblastic leukemia

N/A

TRANSIENT SUBCLONES CARRYING NT5C2 MUTATIONS DEFINE A HIGH-RISK PATIENT GROUP WITH POOR OUTCOME IN PEDIATRIC RELAPSED B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA

Malwine J. Pogodzinski - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

TP53 SOMATIC MUTATIONS AS PRE-LEUKEMIC EVENTS IN ACUTE LYMPHOBLASTIC LEUKEMIA

Guranda Chitadze - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

TP53

EXPRESSION OF PHOSPHORYLATED AKT AND CLASS I PI3K ISOFORMS IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA

Marilena Lourou - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

GENOTYPE AND CLINICAL REPERCUSSIONS IN T LINEAGE ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN

Sidharth Totadri - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

TRIADIC FUSIONS AMONG ZNF384, EWSR1 AND EHMT1 GENES IN A PEDIATRIC B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA PATIENT WITH PH LIKE CHROMOSOME

Xue Chen - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

SHOULD THE B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA WITH MATURE PHENOTYPE AND KMT2A REARRANGEMENTS BE CONSIDERED AS A NEW ENTITY?

Gloria Hidalgo Gomez - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

RELEVANCE OF TPMT, NUDT15 AND ABCC4 GENOTYPING IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA/LYMPHOMA

Eduarda Couto - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

6-mercaptopurine

WHOLE EXOME SEQUENCING IN ADULT PATIENT WITH PHILADELPHIA / BCR-ABL1 POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA

Phan Chin Lee - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Acute lymphoblastic leukemia

N/A

CHARACTERIZATION OF A DUX4-IGH INHIBITOR AS A POSSIBLE TREATMENT FOR ACUTE LYMPHOBLASTIC LEUKEMIA

Mara Salome' - European Hematology Association (EHA) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Acute lymphoblastic leukemia

N/A

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