App-Quantinova.ai

Microthrombocytopenia Accompanied by Cytoskeletal Defects in Platelets Lacking the Small GTPase RhoB

K. Aurbach - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

N/A

Novel Single Cell Mechanobiology Approach Reveals an Intermediate State of Integrin αIIbβ3 that Mediates Platelet Aggregation under Blood Flow Disturbance

L.A. Ju - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

N/A

Shear Rate Gradients Promote a Bi‐phasic Thrombus Formation in a Vwf‐dependent Manner

N. Receveur - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

Fibrinogen (IV)

Characterization of a Novel GPIbα Knockin Mouse that Lacks the Last 24 Amino Acids of its Intracellular Domain

I.I. Salles-Crawley - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

N/A

Novel NADPH Oxidase 1‐selective Inhibitors Impair Collagen‐dependent Platelet Activation and Thrombus Formation in vitro and Ferric Chloride‐induced Carotid Occlusion in vivo with Negligible Effects on Thrombin Responses and Bleeding Time

D. Vara - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

Evithrom

First Generation PI3KC2α Inhibitors are Potently Anti‐Thrombotic and Improve on the Safety Profile of Current Anti‐Platelet Therapies

M. Moon - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

N/A

Neutrophils Are Responsible for Colitis‐induced Anemia and Thrombosis in P2X1‐deficient Mice

C. Oury - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Venous thrombosis

Erythropoietin

Novel Assay Demonstrates Increased Procoagulant Platelet Response in Essential Thrombocythemia Segregating With JAK2V617F Mutation Status and Thrombosis

C.W. Tan - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Venous thrombosis

Thrombomodulin alfa

Thrombosis in Heparin‐induced Thrombocytopenia Is Mediated by Neutrophils

J. Perdomo - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

Heparin

Dissecting the Mechanisms of Thrombocytopenia and Thrombosis in HIT

H. Leung - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

Heparin

Increased Risk of Thrombosis in Antiphospholipid Syndrome Patients Treated with Direct Oral Anticoagulants. Results from an International Patient‐level Data Meta‐analysis

V. Dufrost - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Venous thrombosis

N/A

Predictive Value of Thrombocytopenia in Antiphospholipid Syndrome

T. Moulinet - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Venous thrombosis

N/A

Haemostatic Biomarkers for Prediction of Therapy Response and Prognosis of Disease in Patients with Metastatic Colorectal Cancer

F. Moik - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

Bevacizumab

Hemostatic and Non‐hemostatic Functions of Magnesium Transporter MAGT1 in Mice

E. Mammadova-Bach - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Venous thrombosis

Hemostatic Solution

Role of Neutrophils and Neutrophil Extracellular Traps in Mice Bearing Human Pancreatic Tumors

Y. Hisada - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

N/A

A Validation, with New Clinical Applicability, of a Clinical‐genetic Risk Model that Predicts Thrombosis with High Sensitivity in Patients with Lymphoma

M. Bastos - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Venous thrombosis

N/A

Subsequent Venous Thromboembolism after Upper Extremity Deep Venous Thrombosis in Patients with Cancer

T. Wun - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Venous thrombosis

N/A

Tissue Factor and Tissue Factor in Combination with Alpha‐1 Antitrypsin or Reg4 Associate with Venous Thromboembolism in Patients with Colorectal Cancer

R. van Beijnum - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Venous thrombosis

Alpha 1-Antitrypsin

Two Weeks of Low Molecular Weight Heparin for Isolated Symptomatic Distal Vein Thrombosis (TWISTER Study): Interim Analysis of First 200 Patients

E. Merriman - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

rivaroxaban

The Influence of Renal Impairment on Clinical Outcomes in Venous Thromboembolism Patients Enrolled in GARFIELD‐VTE

S. Goto - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2019

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Venous thrombosis

N/A

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7277 Abstracts