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Sarilumab, a Subcutaneously-Administered, Fully-Human Monoclonal Antibody Against The IL-6 Receptor Alpha: Using Acute Phase Reactants, Efficacy and Safety Parameters To Inform Phase 3 Dose Selection

Janet van Adelsberg - American College of Rheumatology (ACR) , 2013

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Systemic inflammation

Fibrinogen (IV)

Serological Markers Of Structural Integrity and Inflammation Is Associated With Pain In Osteoarthritis

Anne Sofie Siebuhr - American College of Rheumatology (ACR) , 2013

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Osteoarthritis

N/A

Systemic Inflammation Contributes To Depression In Patients With Rheumatoid Arthritis

Mary Margaretten - American College of Rheumatology (ACR) , 2013

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Systemic inflammation

N/A

The Role Of Low-Grade Inflammation In The Association Between Uric Acid and Atherosclerosis: The Codam Study

Jose M.A. Wijn - American College of Rheumatology (ACR) , 2013

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Coronary Artery Disease

sICAM-1

Vitamin D Deficiency Is Common and Associated With Increased C-Reactive Protein In Children With Lupus: An Atherosclerosis Prevention In Pediatric Lupus Erythematosus Substudy

Angela B. Robinson - American College of Rheumatology (ACR) , 2013

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Vitamin D deficiency

Atorvastatin

Active and Structural Lesions on MRI of the Sacroiliac Joints Predict Major Clinical Responses in Patients with Non-Radiographic Axial Spondyloarthritis Treated with Etanercept

Walter P. Maksymowych - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Non-radiographic axial spondyloarthritis

Etanercept

Adiposity and Adipokines Are Associated with Insulin Resistance in Pediatric Systemic Lupus Erythematosus

Leandra Uribe Woolnough - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Lupus

N/A

Antibodies to Citrullinated Clusterin, Filaggrin, Vimentin, and Fibrinogen Are Associated with Blood Pressure in First-Degree Relatives of Rheumatoid Arthritis Patients: The Studies of the Etiology of Rheumatoid Arthritis

Jan M. Hughes-Austin - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Rheumatoid arthritis

Fibrinogen (IV)

Collagen II Neo-Epitopes in Spondyloarthritis.

Heidi Lausten Munk - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Spondyloarthritis

N/A

Coronary-Artery Atherosclerosis in Males with Systemic Lupus Erythematosus

Juanita Romero-Diaz - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Lupus

Oraprine

Evaluation of the Patient Acceptable Symptom State in Patients with Psoriatic Arthritis

Pinar Cetin - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Ankylosing spondylitis

N/A

How Should We Calculate the ASDAS If the Conventional C-Reactive Protein Is below the Limit of Detection? an Analysis in the DESIR Cohort

Pedro Machado - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Axial spondyloarthritis

N/A

Identification of an Inflammation-Driven Phenotype of Osteoarthritis By Quantification of Synovial Inflammation Ex Vivo and in Serum from Patients

Cecilie F. Kjelgaard-Petersen - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

N/A

Interleukin-1 Dual-Variable Domain Immunoglobulin Reduces Multiple Inflammatory Markers in Knee Osteoarthritis Patients

Susanne X. Wang - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Knee osteoarthritis

Interleukin

Periostin May Have a Role in Ankylosing Spondylitis and It Is Associated with Wnt Signalling Pathway Regulators

Servet Akar - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Ankylosing spondylitis

Interleukin

Secukinumab, a Human AntiInterleukin-17A Monoclonal Antibody, Significantly Reduces Psoriasis Burden in Patients with Psoriatic Arthritis: Results from a Phase 3 Randomized Controlled Trial

Alice B. Gottlieb - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Gastroenterology (GU)

Psoriatic arthritis

secukinumab

Secukinumab, a Monoclonal Antibody to Interleukin-17A, Significantly Improves Signs and Symptoms of Active Ankylosing Spondylitis: Results of a 52-Week Phase 3 Randomized Placebo-Controlled Trial with Intravenous Loading and Subcutaneous Maintenance Dosing

Dominique L. Baeten - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Ankylosing spondylitis

secukinumab

Secukinumab, a Monoclonal Antibody to Interleukin-17A, Significantly Improves Signs and Symptoms of Active Ankylosing Spondylitis: Results of a Phase 3, Randomized, Placebo-Controlled Trial with Subcutaneous Loading and Maintenance Dosing

Joachim Sieper - American College of Rheumatology (ACR) , 2014

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Ankylosing spondylitis

secukinumab

Ultrasensitive C reactive protein is a marker of endoscopic relapse in patients with ulcerative colitis

W. Cedillo-Suarez - European Crohn’s and Colitis Organisation (ECCO) , 2013

Therapeutic Area

Disease

Drug/Treatment

Dermatology

Ulcerative colitis

N/A

Anti-MAdCAM monoclonal antibody PF-00547659 does not affect immune surveillance in the central nervous system of anti-TNF and immunosuppressant experienced Crohn's disease patients who are anti-TNF inadequate responders: Results from the TOSCA stud

S. Vermeire - European Crohn’s and Colitis Organisation (ECCO) , 2014

Therapeutic Area

Disease

Drug/Treatment

Gastroenterology (GU)

Crohn's disease

Oraprine

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1408 Abstracts