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Predictive biomarkers of tumor sensitivity to STEAP1 antibody-drug conjugate (ADC) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC)

Daniel C. Danila - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Metastatic castration-resistant prostate cancer

N/A

Latent class longitudinal modeling of CTCs in ER+ metastatic breast cancer patients

Terry Hyslop - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Breast cancer

N/A

Distinct nuclear translocation mechanism of androgen receptor variant ARv7

Seaho Kim - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Prostate cancer

Enzalutamide

Androgen receptor expression reduces post-hepatectomy surgery recurrence risks of hepatocellular carcinoma

Wen-Lung Ma - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Liver cancer

Androgen Tear

Sub-classification of prostate cancer circulating tumor cells (CTCs) by nuclear size reveals very-small nuclear CTCs in patients with visceral metastases

Jie-Fu Chen - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Prostate cancer

Mifepristone

Correlations of COX2 expressions in circulating tumor cells (CTCs) and response to radiotherapy in head and neck squamous cell carcinoma (HNSCC)

Feng Wang - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Squamous cell carcinoma of the head and neck

Prostaglandin

Preclinical evaluation and biomarker identification for the anti-LGR5 mAb BNC101 in K-Ras mutant CRC and other solid tumor indications

Peter Chu - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Colorectal Cancer

BNC101

A novel method to quantify gamma H2AX foci in circulating tumor cells in patients receiving chemotherapy for colorectal cancer

Matilde Saggese - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Colorectal Cancer

Fluorescein sodium

Multiplexed ICE COLD-PCR coupled to NGS and ddPCR enables enhanced detection of low-level DNA mutations in tissues and liquid biopsies

Katherine Anne Richardson - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Melanoma

N/A

Upregulation of mRNA of CD80, FOXP3, NKG2D and PD-L1 in peripheral blood mononuclear cells is associated with metastatic breast cancer patients

Ayane Yamaguchi - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Breast cancer

N/A

Renal cell carcinoma patients have altered HLA expression patterns which show correlations to clinical parameter

Steffen Goebel - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Renal cell carcinoma

N/A

Enrichment and isolation of uncontaminated breast cancer cells from human blood samples

Sandra V. Fernandez - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Breast cancer

N/A

Label-free concentration of viable breast cancer CTCs for single cell Western blotting

Elly Sinkala - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Breast cancer

N/A

Mitophagy imparts enzalutamide resistance in prostate cancer

Hirak S. Basu - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Prostate cancer

CB-7598

Aggressive breast cancer associated fibroblasts communicate with cancer cells via microRNAs and promote an aggressive breast cancer phenotype

Sanket Shah - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Breast cancer

miR155

Simple modifications in Ion Torrent Variant Caller (TVC) parameters improve somatic variant detection from circulating tumor cells and cell free DNA to 1% allele frequency

Colin Davidson - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Genomic cytometry: Single cell mutation analysis combining PCR with flow cytometry

William C. Hyun - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Prostate cancer

N/A

Characterization of genetic concordance between primary tumor cells, circulating tumor cells, and metastatic tumor cells from patients with prostate cancer

Lixin Yang - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Prostate cancer

N/A

Dissecting CTC phenotypes: insights into mechanisms of breast cancer dormancy

Sirisha Peddibhotla - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Brain metastasis

N/A

Mobilizing prostate cancer cells from the endosteal niche by targeting the SDF-1/CXCR4 axis

Kenneth C. Valkenburg - American Association for Cancer Research (AACR) , 2015

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Prostate cancer

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