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: The Immature Morphology of the Megakaryocytes Present in the Bone Marrow of Patients with Myelofibrosis Reflects Changes in the Frequency of Functionally Distinctive Subpopulations

Researchers

Presenter

  • Francesca Arciprete

Principal Investigators

  • Maria Zingariello

  • Maria Mazzarini

  • Paola Verachi

  • Fabrizio Martelli

  • Anna Crescenzi

  • Elisabetta Cerchiara

  • Giuseppe Avvisati

  • Paola Guglielmelli

  • Manjola Balliu

  • Alessandro Vannucchi

  • Anna Rita Migliaccio

Medical Centers

  • National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy

  • Unit of Microscopic and Ultrastructural Anatomy, Dept of Medicine, University Campus Bio-Medico Roma, Rome, Italy

  • Medicine and Surgery, University Campus Bio-Medico, Rome, Italy

  • Universita Campus Bio-Medico, Rome, ITA

  • Department of Hematology, Stem Cell Transplantation, Campus Bio-Medico University Hospital, Rome, Italy

  • Altius Institute for Biomedical Sciences, Seattle, WA

  • CRIMM, Center of Research and Innovation of Myeloproliferative Neoplasms, University of Florence, AOU Careggi, Florence, Italy

  • Azienda Ospedaliero Universitaria Careggi, Florence, Italy

  • Biomedical and Neuromotorial Sciences, Alma Mater Studiorum University, Bologna, Italy

  • Campus Bio-Medico University, Rome, ITA

  • University of Florence, Azienda Ospedaliero Universitaria Careggi, CRIMM, Florence, Italy

Locations

  • Italy

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

  • Oncology (ONC)

Disease

  • Hematological malignancies

  • Essential thrombocythemia

  • Myelofibrosis

Biomarkers

  • Aryl hydrocarbon receptor nuclear translocator-like protein 1

  • Platelet Factor 4

  • Collagen alpha-1(I) chain

  • Collagen Type III Alpha 1 Chain

  • Transforming growth factor beta

Drug/Treatment

  • Interleukin

Outcome

  • N/A

Study Design

  • Bioavailability

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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