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: Mesenchymal Stromal Cells Protect Acute Myeloid Leukemia Cells from Venetoclax-Induced Apoptosis through Contact-Dependent Mechanisms

Researchers

Presenter

  • Giulia Corradi

Principal Investigators

  • Samantha Bruno

  • Gaia Mazzocchetti

  • Jacopo Nanni

  • Andrea Polimeno

  • Michele Cavo

  • Marilena Ciciarello

  • Antonio Curti

Medical Centers

  • IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia Seragnoli, Bologna, Italy

  • Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università di Bologna, Bologna, Italy

  • Dipartimento di Medicina e Scienze dell'Invecchiamento, Università di Chieti-Pescara, Chieti-Pescara, Italy

Locations

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute myelocytic leukemia

  • B cell lymphomas

  • Lymphomas

Biomarkers

  • B-cell lymphoma 2

  • C-X-C motif chemokine receptor 4

  • Granulin precursor

  • Mesenchymal stem cells

  • Thy-1 Cell Surface Antigen

Drug/Treatment

  • Venetoclax

  • Trypsin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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