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: Fatalities from Tumor Lysis Syndrome (TLS) after Anti-Hyperuricemic Monotherapy - Nationally Representative, Propensity Score Matched, Retrospective Study Comparison of Rasburicase and Allopurinol

Researchers

Presenter

  • Mitchell S Cairo

Principal Investigators

  • Jack R Gallagher

  • Yvonne Barnes

  • Edward Drea

  • Susan Carroll

Medical Centers

  • New York Medical College, Departments of Pediatrics, Medicine, Pathology, Microbiology and Immunology, and Cell Biology and Anatomy, Maria Fareri Children's Hospital at Westchester Medical Center, Valhalla, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Endocrine/metabolic Diseases (ME)

  • Nephrology

Disease

  • Tumor lysis syndrome

  • Acute renal failure

  • Renal disease

  • Renal insufficiency

  • Solid malignancies

Biomarkers

  • Creatinine

  • Folate Hydrolase 1

  • RNA-binding protein FUS/TLS

Drug/Treatment

  • Allopurinol

  • Rasburicase

Outcome

  • N/A


Study Design

  • Randomized

  • Double Blind/Blinded

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A