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: Gene Expression Profiling and Signaling Pathway Analysis of Tolerant T Cells Circulating in Adult Patients after Ptcy Haplotransplantation

Researchers

Presenter

  • Paul Szabolcs

Principal Investigators

  • Taylor Nee

  • Xiaohua Chen

  • Dhivyaa Rajasundaram

  • Rafic J. Farah

Medical Centers

  • Division of Health Informatics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA

  • Division of Blood and Marrow Transplantation and Cellular Therapies, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA

  • UPMC Hillman Cancer Center, Pittsburgh, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Autoimmune (AI)

Disease

  • Myelodysplastic Syndrome

  • Graft-versus-host disease

Biomarkers

  • Adenomatous Polyposis Coli

  • Phosphatase and tensin homolog

  • Cluster of Differentiation 2AP

  • CREB-binding protein

  • Cytokine

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon

  • Regulatory T cells

  • T-cell receptor

Drug/Treatment

  • E7272

  • Cytoxan oral and injection

  • Nivolumab

  • Tacrolimus

Outcome

  • N/A

Study Design

  • Adaptive

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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