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: Collections of Autologous Lymphocytes for Treatment with Chimeric Antigen Receptor (CAR) T-Lymphocytes - No Association of Clonal Hematopoiesis (CH) with Manufacturing Success

Researchers

Presenter

  • Simon M. Krauss

Principal Investigators

  • Enrica Bach

  • Mandy Brückner

  • Anne Weigert

  • Theresa Tumewu

  • Florian Ramdohr

  • Elena Ruschpler

  • Gunhild Vogtmann

  • Sandra Hoffmann

  • Olaf Penack

  • Martin Janz

  • Raymund Buhmann

  • Reinhard Henschler

  • Lars Bullinger

  • Ulrich Keller

  • Sebastian Schwind

  • Maximilian Merz

  • Madlen Jentzsch

  • Georg-Nikolaus Franke

  • Marco Herling

  • Uwe Platzbecker

  • Klaus H. Metzeler

  • Vladan Vucinic

Medical Centers

  • Department of Hematology, Oncology and Tumorimmunology (Campus Benjamin Franklin), Charite University Berlin, Berlin, Germany

  • Department of Hematology, Cell Therapy and Hemostaseology, University Hospital Leipzig, Leipzig, Germany

  • Institute for Transfusion Medicine, University Hospital Leipzig, Leipzig, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Diffuse large B-cell lymphoma

  • Acute lymphoblastic leukemia

  • Follicular lymphoma

  • Myeloid neoplasms

  • B cell lymphomas

  • Lymphomas

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of Differentiation 4

  • Cluster of Differentiation 2AP

  • Coxsackie Virus And Adenovirus Receptor

  • Cluster of differentiation 8A

  • DNA methyltransferase 3 alpha

  • Tet methylcytosine dioxygenase 2

  • Tumor protein p53

Drug/Treatment

  • tisagenlecleucel-t

  • Bendamustine

  • TP53

Outcome

  • N/A

Study Design

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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