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: Dual CAR Stimulation in CD19xCD22 Bicistronic CAR T Cells Results in Increased c-Jun Expression and Superior In Vivo Expansion

Researchers

Presenter

  • Alexander W. Rankin

Principal Investigators

  • Mark Eric Kohler

Medical Centers

  • Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Blood/haematological Diseases

Disease

  • Acute lymphoblastic leukemia

  • Non-Hodgkin's Lymphoma

  • Non‐Hodgkin Lymphoma

  • B cell lymphomas

  • Hodgkin's Lymphoma

  • Lymphomas

Biomarkers

  • p38 Mitogen-activated protein kinases

  • Mitogen-activated protein kinase

  • Breakpoint Cluster Region

  • Coxsackie Virus And Adenovirus Receptor

  • Extracellular signal-regulated kinase

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Efficacy

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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