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: Characterization of a Cyclic Dinucleotide Metabolic Switch to Fuel Antitumor Immunity

Researchers

Presenter

  • Jeremy A. Meier

Principal Investigators

  • Katie E. Hurst

  • David L. Corcoran

  • Jessica E. Thaxton

  • Jonathan S. Serody

Medical Centers

  • Department of Microbiology & Immunology, University of North Carolina, Chapel Hill, NC

  • Department of Genetics, University of North Carolina, Chapel Hill, NC

  • Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC

  • Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC

  • Department of Medicine, Division of Hematology, University of North Carolina, Chapel Hill, NC

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Autoimmune (AI)

Disease

  • Breast cancer

  • Solid malignancies

  • Lymphomas

  • Graft-versus-host disease

Biomarkers

  • Acetyl-CoA carboxylase

  • AMP-activated protein kinase

  • Coxsackie Virus And Adenovirus Receptor

  • T cell activity

Drug/Treatment

  • Interferon

Outcome

  • N/A

Study Design

  • Efficacy

  • Immunogenicity

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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