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: Inhibition of MICA and MICB Shedding Enhances Cytokine-Induced Memory-like NK Cell-Mediated Activity Against Multiple Myeloma

Researchers

Presenter

  • Sabrin Tahri

Principal Investigators

  • Luisa Maria Lampe

  • Han Dong

  • Juliana Vergara Cadavid

  • Natalie Papazian

  • Amanda Cao

  • Jean-Baptiste Alberge

  • Lucas Ferrari de Andrade

  • Mahshid Rahmat

  • Yujia Shen

  • Rebecca Boiarsky

  • Laura Blanco

  • Bruno Paiva

  • Andreas Guenther

  • Gad Getz

  • Pieter Sonneveld

  • Tom Cupedo

  • Kai W. Wucherpfennig

  • Irene Ghobrial

  • Rizwan Romee

Medical Centers

  • CSAIL and IMES, Massachusetts Institute of Technology, Cambridge, MA

  • Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA

  • Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

  • Kiel University, Faculty of Medicine, Kiel, Germany

  • Dana-Farber Cancer Institute, Boston, MA

  • Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands

  • Department of Medicine, Yong Loo Lin School of Medicine, Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore

  • Erasmus MC Cancer Institute, department of Hematology, Rotterdam, Netherlands

  • University of Navarra, IDISNA, CIBERONC, Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Pamplona, Spain

  • Department of Oncological Sciences, Icahn School of Medicine at the Mount Sinai Hospital, New York

  • Broad Institute of MIT and Harvard, Cambridge, MA

  • Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

  • Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA

  • Clinica Universidad de Navarra, Cancer Center Universidad de Navarra (CCUN), Centro de Investigación Medica Aplicada (CIMA), Instituto de Investigación Sanitaria de Navarra (IDISNA), Navarra, Spain

Locations

  • United States

  • Netherlands

  • Germany

  • Spain

  • Singapore

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Multiple Myeloma

Biomarkers

  • Natural Killer cells

  • Interferon-gamma

  • Natural killer group 2D

Drug/Treatment

  • Bortezomib

  • Interferon Gamma

  • IFN-lambda

Outcome

  • N/A

Study Design

  • Efficacy

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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