// App-Quantinova.ai

: CD8+ T Cells from Patients with CLL Show Evidence of Granzyme B and Perforin Cytotoxic Capacity, Which Is Enhanced upon Exposure to Exogenous IL2 and/or IL21

Researchers

Presenter

  • Cristina Paraschivescu

Principal Investigators

  • Shivani Chhabra

  • Rukhsana Aslam

  • Byeongho Jung

  • Gerardo Ferrer

  • Jacqueline C. Barrientos

  • Joanna M. Rhodes

  • Jonathan E. Kolitz

  • Steven L Allen

  • Kanti R Rai

  • Barbara Sherry

  • Nicholas Chiorazzi

Medical Centers

  • Cancer Epigenetics, Josep Carreras Leukaemia Research Institute (IJC), Badalona, Spain

  • Center for Immunology and Inflammation, The Feinstein Institute for Medical Research, Northwell Health System, Manhasset, NY

  • Karches Center for Oncology Research, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY

  • Department of Medicine, North Shore University Hospital and Long Island Jewish Medical Center, Northwell Health, Manhasset, NY

  • Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY

  • Departments of Medicine and of Molecular Medicine, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY

Locations

  • Spain

  • United States

  • New Zealand

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Perforin 1

  • Peripheral blood mononuclear cell

  • Cluster of Differentiation 107 Antigen-Like Family Member A

  • Cluster of differentiation 8A

  • Granzyme B

  • Interleukin-2

  • Interleukin-21

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved