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: Dual Inhibition of NF-Kb and JAK/STAT Pathways Reverts Myelofibrosis-like Phenotype in an In Vivo Murine Model

Researchers

Presenter

  • Ernesto J Cuenca

Principal Investigators

  • Pedro J Guijarro-Carrillo

  • María J López-Poveda

  • Paula Durán-Espin

  • Eva Soler

  • Maria Luz Morales

  • Maria Luisa Lozano

  • Alberto Alvarez-Larran

  • Nuria Garcia-Barbera

  • Rocio Gonzalez-Conejero

  • Constantino Martinez

  • Raul Teruel Montoya

  • Francisca Ferrer Marin

Medical Centers

  • Hematology Department, Hospital Clínic, Barcelona, Spain

  • UCAM, Murcia, Spain

  • Servicio de Anatomía Patológica. H.U. Morales Meseguer, Murcia, Spain

  • Servicio de Hematología y Oncología Médica. H.U. Morales Meseguer. Centro Regional de Hemodonación. Universidad de Murcia. IMIB-Arrixaca, Murcia, Spain

  • CIBERER U-, Murcia, Spain

  • Centro Regional De HemodonacióN, Murcia, Spain

Locations

  • Spain

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Myelofibrosis

Biomarkers

  • Cluster of Differentiation 19

  • Janus kinase

Drug/Treatment

  • Ruxolitinib phosphate

  • BMS-345541

  • Pacritinib

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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