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: The Composition, Cell Interaction Patterns and Prognostic Impact of the Tumor Microenvironment in Germinal Center B-Cell and Activated B-Cell-like Diffuse Large B-Cell Lymphoma

Researchers

Presenter

  • Matias Autio

Principal Investigators

  • Suvi-Katri Leivonen

  • Oscar Bruck

  • Marja-Liisa Karjalainen-Lindsberg

  • Teijo Pellinen

  • Sirpa Leppa

Medical Centers

  • Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland

  • Research Programs Unit, Applied Tumor Genomics, Faculty of Medicine, University of Helsinki, Helsinki, Finland

  • Helsinki University Hospital, Helsinki, Finland

  • Institute for Molecular Medicine Finland, Helsinki, Finland

Locations

  • Finland

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Diffuse large B-cell lymphoma

Biomarkers

  • beta-2 microglobulin

  • Natural Killer cells

  • B-lymphocyte antigen CD20

  • Cluster of Differentiation 163

  • Cluster of Differentiation 4

  • Cluster of Differentiation 2AP

  • Forkhead Box P3

  • Cluster of Differentiation 56

  • Programmed cell death protein 1

  • Programmed death-ligand 1

  • Cluster of differentiation 8A

  • Granzyme B

  • Human Leukocyte Antigen – DR isotype

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • Vincristine

  • Doxorubicin

  • Prednisone

  • Rituximab

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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