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: Recurrent DNMT3B Alterations Are Associated with Unfavorable Outcome in Dicentric (9;20)-Positive Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Zeljko Antic

Principal Investigators

  • Alena van Bömmel

  • Konstantin Riege

  • Jana Lentes

  • Charlotte Schröder

  • Julia Alten

  • Lara Fuhrmann

  • Martin Zimmermann

  • Cornelia Eckert

  • Gunnar Cario

  • Martin Schrappe

  • Brigitte Schlegelberger

  • Steve Hoffmann

  • Anke K. Bergmann

Medical Centers

  • Department of Human Genetics, Hannover Medical School (MHH), Hannover, Germany

  • Department of Pediatric Oncology and Hematology, Charité University Medical Center, Berlin, Germany

  • Department of Pediatric Hematology and Oncology, Hannover Medical School (MHH), Hannover, Germany

  • Leibniz Institute on Ageing-Fritz Lipmann Institute (FLI), Jena, Germany

  • Department of Pediatrics, Berlin-Frankfurt-Münster ALL Study Group Germany (BFM-G), University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Paired box 5

Drug/Treatment

  • Prednisone

Outcome

  • N/A


Study Design

  • Cohort

  • Global

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A