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: Preclinical In Vivo Activity of the Menin Inhibitor Ziftomenib (KO-539) in Pediatric KMT2A-Rearranged Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Catherine D Falkenstein

Principal Investigators

  • Lisa M Niswander

  • Linda Kessler

  • Blake Tomkinson

  • Francis Burrows

  • Sarah K Tasian

Medical Centers

  • Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA

  • Department of Pediatrics and Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA

  • Kura Oncology, San Diego, CA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of Differentiation 19

  • Cluster of differentiation 45

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Vincristine

Outcome

  • N/A

Study Design

  • Randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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