// App-Quantinova.ai

: Niclosamide Inhibits the Growth of Acute Lymphoblastic Leukemia Cells By Increasing Intracellular ROS and Activation of p53-PUMA/NOXA

Researchers

Presenter

  • Junbin Huang

Principal Investigators

  • Jing Yang

  • Yun Chen

  • Zhizhuang Joe Zhao

  • Chun Chen

Medical Centers

  • Sun Yat-Sen University, Shenzhen, China

  • Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK

  • pediatric, the seventh affiliated hospital, Sun Yat-sen University, shenzhen, China

  • Moores Cancer Center, University of California, San Diego, La Jolla, CA

Locations

  • China

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Musculoskeletal

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of Differentiation 19

  • Cluster of differentiation 45

  • Proto-oncogene tyrosine-protein kinase ROS

Drug/Treatment

  • N-acetylcysteine

  • niclosamide

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved