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: PIM Kinases Regulate Super-Enhancer-Dependent Gene Expression in Diffuse Large B-Cell Lymphoma

Researchers

Presenter

  • Sonia Debek

Principal Investigators

  • Dorota Komar

  • Filip Garbicz

  • Aleksandra Matrejek

  • Michał Pawlak

  • Ewa Jabłońska

  • Maciej Szydlowski

  • Magdalena Skrzypczak

  • Sylwia Radomska

  • Daniela Bellarosa

  • Nazli Serin

  • Malgorzata Bajor

  • Bjoern Chapuy

  • Przemyslaw Juszczynski

Medical Centers

  • Department of Hematology, Oncology and Tumor Immunology, Charité University Medical Center Berlin, Berlin, Germany

  • Department of Molecular Biology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland

  • Laboratory of Immunology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland

  • Department of Hematology and Medical Oncology, University of Medical Center Göttingen, Göttingen, Germany

  • Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Warszawa, Poland

  • Postgraduate School of Molecular Medicine, Medical University of Warsaw, Warsaw, Poland

  • Experimental and Translational Oncology Department, Menarini Ricerche S.p.A., Pomezia (rome), Italy

  • Centre for Omic Sciences (COS), Eurecat, Centre Tecnològic de Catalunya, Reus, Spain

  • Department of Clinical Immunology, Medical University of Warsaw, Warsaw, Poland

Locations

  • Germany

  • Spain

  • Poland

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Diffuse large B-cell lymphoma

  • Solid malignancies

Biomarkers

  • Histone Acetyltransferase KAT8

  • Fms related tyrosine kinase 3

  • Apparent diffusion coefficient

Drug/Treatment

  • Sandolase

Outcome

  • N/A


Study Design

  • Controlled

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A