// App-Quantinova.ai

: Efficacy and Safety of Avatrombopag in Combination with Immunosuppressive Therapy in Treatment-Naïve and Relapsed/Refractory Severe Aplastic Anaemia - the Diaamond-Ava-First and Diaamond-Ava-Next Bayesian Optimal Phase II Trials

Researchers

Presenter

  • Zoe McQuilten

Principal Investigators

  • Vanessa Fox

  • Stephane Heritier

  • Tracey J Batt

  • Piers Blombery

  • Jennifer Curnow

  • Alisa Higgins

  • Devendra Hiwase

  • Robin J Filshie

  • Frank Firkin

  • Paul Lacaze

  • Kylie D Mason

  • Tony Mills

  • Sushrut S. Patil

  • Dominic Pepperell

  • William S Stevenson

  • Jeffrey Szer

  • Neil Waters

  • Kate Wilson

  • Stephen B Ting

  • Erica M. Wood

Medical Centers

  • Department of Clinical Haematology, Monash Health, Melbourne, Australia

  • University of Sydney, Sydney, Australia

  • Department of Hematology, St. Vincent's Hospital Melbourne, Melbourne, Australia

  • Department of Haematology, Eastern Health and Monash University, Melbourne, Australia

  • Monash Haematology, Monash Health, Clayton, Australia

  • Public Health and Preventative Medicine, Monash University, Melbourne, Australia

  • Peter MacCallum Cancer Centre, Peter Maccallum Cancer Centre, East Melbourne, Australia

  • Royal Hobart Hospital, Hobart, Australia

  • Department of Haematology, Fiona Stanley Hospital, Murdoch, Australia

  • Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia

  • Department of Medicine, University of Melbourne, Melbourne, Australia

  • Alfred Hospital, Melbourne, AUS

  • Department of Clinical Haematology, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Melbourne, Australia

  • University of Queensland, Brisbane, Australia

  • St Vincent's Hospital, Melbourne, Australia

  • Transfusion Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

  • Department of Haematology, Westmead Hospital, Western Sydney Local Health District, Sydney, Australia

  • Peter MacCallum Cancer Centre, MELBOURNE, Australia

  • Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia

  • Department of Haematology, Royal North Shore Hospital, Sydney, Australia

  • MONASH UNIVERSITY, Melbourne, Australia

Locations

  • Australia

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • T-cell receptor

Drug/Treatment

  • Avatrombopag

  • Cyclosporine A

  • anti-thymocyte equine

Outcome

  • N/A

Study Design

  • Randomized

  • Efficacy

  • Safety

  • Adaptive

  • Single Arm

  • Non Randomized

  • Tolerability

  • Global

  • Investigator Initiated

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved