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: Restored Biosynthetic Pathways Induced By MSCs Serve As Rescue Mechanism in Leukemia Cells after L-Asparaginase Therapy

Researchers

Presenter

  • Natividad Alquezar-Artieda

Principal Investigators

  • Jennie Roberts

  • Daniela Kuzilkova

  • Katerina Hlozkova

  • Alena Pecinova

  • Petr Pecina

  • Martina Zwyrtkova

  • Eliska Potuckova

  • Daniel Kavan

  • Ivana Hermanova

  • Marketa Zaliova

  • Petr Novak

  • Tomas Mracek

  • Daniel A Tennant

  • Jan Trka

  • Julia Starkova

Medical Centers

  • Institute of Microbiology, Academy of Science, Prague, Czech Republic

  • Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham, GBR

  • Hypoxia and Metabolism Group, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, United Kingdom

  • Department of Bioenergetics, Institute of Physiology of the Czech Academy of Sci, Prague, CZE

  • CLIP - Childhood Leukaemia Investigation Prague, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic

Locations

  • Czech Republic

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Mesenchymal stem cells

Drug/Treatment

  • Asparaginase

  • Glutamine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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