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: Clonal Competition: Cisplatin Treatment Drives Dominance of TP53- over Tet2-Mutant Stem Cell Clones

Researchers

Presenter

  • Katharina Wohlan

Principal Investigators

  • Joanne I. Hsu

  • Katie A. Matatall

  • Rebecca L. Murdaugh

  • Linda Zhang

  • Anna Guzman

  • Jack Toups

  • Daniel Hormaechea-Agulla

  • Carina Rosas

  • Meghan Kisiel

  • Ayumi Kitano

  • Tianyuan Hu

  • Yu-Jung Tseng

  • Bailee N. Kain

  • Sara Biesiadny

  • Jonathan Tiessen

  • Minhua Li

  • Marcus Florez

  • Sarah Waldvogel

  • Kristen Kurtz

  • Mira Jeong

  • Duy Le

  • Daniel E. Morales-Mantilla

  • Hannah Yan

  • Alejandra Garcia Martell

  • Chiraag D. Kapadia

  • Yung-Hsin Huang

  • Shannon E. Conneely

  • Rogelio Aguilar

  • Xiangguo Shi

  • Tianpeng Gu

  • Hyojeong Han

  • Yajian Jiang

  • Jason Rogers

  • Taishi Yonezawa

  • Apoorva Thatavarty

  • Ruoqiong Cao

  • Trisha K. Wathan

  • Nesa Mercer

  • Daniel Kennedy

  • Ayala Tovy

  • Jaime M. Reyes

  • Marek Kimmel

  • Yun Huang

  • Daisuke Nakada

  • Katherine Y. King

  • Margaret A. Goodell

Medical Centers

  • Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston

  • Department of Statistics, Rice University, Houston

  • Translational Biology and Molecular Medicine Graduate Program, Baylor College of Medicine, Houston

  • Texas Children's Hospital, Houston

  • Department of Pediatrics, Baylor College of Medicine, Houston

  • Center for Cell and Gene Therapy, Baylor College of Medicine, Houston

  • Department of Pediatrics, Division of Infectious Diseases, Baylor College of Medicine, Houston, TX

  • Institute of Biosciences and Technology, Texas A&M University, Houston

  • Department of Pediatrics, Section of Hematology/Oncology, Baylor College of Medicine, Houston, TX

  • Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston

  • Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Tumor protein p53

Drug/Treatment

  • Cisplatin

  • TP53

Outcome

  • N/A


Study Design

  • Active Comparator

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A